期刊文献+

具核梭杆菌与肠道免疫相关性研究进展 被引量:3

Recent advances in relationship of Fusobacterium nucleatum to intestinal immunity
原文传递
导出
摘要 肠道微生物生态系统与免疫系统之间有着密切关系,影响着人们的健康。其中,具核梭杆菌(Fusobacterium nucleatum,Fn)备受关注。近年越来越多的研究发现Fn可促进肠道炎症反应,改变结肠肿瘤的免疫微环境。本文将就具核梭杆菌对肠道免疫的影响及相关疾病研究新进展作一综述,以期寻找Fn相关性肠道疾病的免疫机制,并提供新的免疫治疗靶点。 Gut microbial ecosystem is closely related to the immune system and influences human health. Fusobacterium nucleatum (F.nucleatum) is one of the species of great concern. Increasing evidence shows that F. nucleatum promotes intestinal inflammation and influences the tumor-associated immune microenvironment. This review focused on the recent progress in the influence of F. nucleatum on intestinal immunity and the pathogenesis of intestinal diseases in order to discover the immune mechanism of F. nucleatum-associated intestinal diseases and find new therapeutic targets for immunotherapy.
作者 陈永昱 陈燕 董卫国 Chen Yongyu;Chen Yan;Dong Weiguo(Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China)
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2019年第7期558-562,共5页 Chinese Journal of Microbiology and Immunology
关键词 具核梭杆菌 Fn相关性肠道疾病 肠道免疫 Fusobacterium nucleatum Fusobacterium nucleatum-associated intestinal disease Intestinal immunity
  • 相关文献

同被引文献15

引证文献3

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部