摘要
炎症性肠病(IBD)是发生在肠道的一种特发性炎性疾病。肠道微生物在保持机体肠黏膜屏障功能、调节机体代谢和维持免疫稳态中发挥重要功能,在IBD发生、发展以及治疗中可能发挥的作用已引起研究者的关注。因此,研究IBD的肠道微生物基础,有利于阐明相关发病机制,可能为该疾病的预防、诊断、治疗和预后转归提供新思路。本文综述IBD中关于肠道微生物的研究进展。
Inflammatory bowel disease(IBD)is an idiopathic inflammatory disease affecting the gastrointestinal tract.Gut microbiota play an important role in keeping the intestinal mucosal barrier,regulating body metabolism and maintaining immune homeostasis.The potential role of the microbiome in the development,progression,and treatment of IBD has aroused more attention.Therefore,a better understanding of the role of gut microbiota in IBD may provide better insights for disease prevention,diagnosis,treatment and prognosis,which is important for understanding the pathogenesis.In this review,research of gut microbiota in IBD are summarized.
作者
孙一凡
谭亚芳
潘志远
杨瑞馥
毕玉晶
Sun Yifan;Tan Yafang;Pan Zhiyuan;Yang Ruifu;Bi Yujing(Institute of Microbiology and Epidemiology,Academy of Military Medical Sciences,Academy of Military Sciences,Beijing 100071,China)
出处
《中华炎性肠病杂志（中英文）》
2023年第3期292-296,共5页
Chinese Journal of Inflammatory Bowel Diseases
基金
国家重点研发计划(2021YFC2301000)。
关键词
炎症性肠病
肠道微生物
肠道菌群失调
测序
培养
Inflammatory bowel disease
Gut microbiota
Gut microbiota dysbiosis
Sequencing
Culturomics
