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具核梭杆菌FadA黏附素的研究进展 被引量:5

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摘要 具核梭杆菌(Fusobacteriumnucleatum,Fn)是在牙周微生态环境中常驻的一种革兰阴性专性厌氧杆菌,在健康人群和牙周炎患者口腔中均可检出。Fn可与多种口腔微生物黏附共聚,在龈下菌斑生物膜形成过程中担任“桥梁”分子,对菌斑生物膜的成熟至关重要n,。此外,Fn被认为是一种“黏附型”微生物,可黏附于上皮细胞、成纤维细胞、内皮细胞、多形核白细胞、单核/巨噬细胞等多种宿主细胞表面,并与唾液大分子、细胞外基质蛋白、抗体IgG等结合,
出处 《中华口腔医学杂志》 CAS CSCD 北大核心 2014年第12期770-773,共4页 Chinese Journal of Stomatology
基金 国家自然科学基金(81371150) 留学回国人员科研启动基金(2013-693-11-11)
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参考文献31

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同被引文献67

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