摘要
目的针对酒石酸唑吡坦的用药剂量、用药时间、注意事项等给出安全建议。方法检索相关网站和数据库,对酒石酸唑吡坦的药学特点、临床应用情况、不良反应、药物相互作用及合理使用进行概述。结果为保障患者用药安全,建议女性及65岁及以上的老年人宜使用最低有效剂量5 mg·d^-1;尽量短期使用,服药疗程不宜超过4周;失眠患者可选择按需治疗(间断性、非每夜给药);严格遵医嘱,按照规定的疗程和剂量服用。结论酒石酸唑吡坦可治疗多种类型的失眠,疗效确切,不良反应较轻。临床医生与药师需重视唑吡坦用药安全风险,告知患者使用禁忌和注意事项。
OBJECTIVE To givesafety recommendations for the dose,time of administration,and precautions for zolpidem tartrate. METHODS Search relevant websites and databases,the pharmaceutical characteristics,clinical application,adverse reactions,drug interactions and rational use of zolpidem tartrate were reviewed. RESULTS In order to ensure the safety of medication for patients,it is recommended that women and the elderly aged 65 years and above should use the minimum effective dose of 5 mg·d^-1. Short-term use,the course of medication should not exceed 4 weeks. Insomnia patients can choose to treat as needed( intermittent,not every night). Follow the prescribed course of treatment and dosage in strict accordance with the doctor’s advice. CONCLUSIONS Zolpidem tartrate can treat various types of insomnia with definite curative effect and mild adverse reactions. Clinicians and pharmacists should pay attention to the safety risks of zolpidem and inform patients of the contraindications and precautions.
作者
杨玉慧
许秀丽
朱珠
YANG Yu-hui;XU Xiu-li;ZHU Zhu(Department of Pharmacy, Chinese Academy Medical Sciences & Peking Union Medical College Hospital, Beijing 100730, China)
出处
《中国药学杂志》
CAS
CSCD
北大核心
2019年第14期1188-1193,共6页
Chinese Pharmaceutical Journal
关键词
酒石酸唑吡坦
用药风险
安全警示
合理用药
zolpidem tartrate
medication risk
safety warning
rational drug use
