摘要
目的:探究血清PCT、NLR及外周血T淋巴细胞亚群与脓毒症患者预后的关系。方法:选取2017年1-12月本院收治的80例脓毒症患者为观察组,另选取同时期的80例健康同龄者为对照组。检测与比较对照组及观察组的血清PCT、NLR及外周血T淋巴细胞亚群,同时比较观察组中不同预后与严重程度者的检测结果,并采用Pearson相关性分析处理上述血液指标与脓毒症患者预后的关系。结果:观察组的血清PCT、NLR及CD8^+均高于对照组,其他外周血T淋巴细胞亚群指标均低于对照组,观察组中不同预后与严重程度者的检测结果比较,差异均有统计学意义(P<0.05)。Pearson相关性分析显示,血清PCT、NLR及CD8^+与脓毒症患者预后均呈正相关(P<0.05),其他外周血T淋巴细胞亚群指标与脓毒症患者预后均呈负相关(P<0.05)。结论:血清PCT、NLR及外周血T淋巴细胞亚群在脓毒症患者中呈现异常表达的状态,且与本类患者的预后有密切的关系,因此在脓毒症患者中具有较高的检测价值。
Objective:To investigate the relationship between the serum PCT,NLR,peripheral blood T lymphocyte subsets and prognosis of patients with sepsis.Method:80 patients with sepsis in our hospital from January 2017 to December 2017 were chosen as the observation group,80 healthy persons of the same age at the same time were chosen as the control group.Then the serum PCT,NLR,peripheral blood T lymphocyte subsets of control group and observation group were detected and compared,then the detection results of observation group with different prognosis and severity degree were compared,then the relationship between those blood indexes and prognosis of patients with sepsis were analyzed with Pearson correlation analysis.Result:The serum PCT,NLR and CD8^+of observation group were all higher than those of control group,other peripheral blood T lymphocyte subsets indexes were all lower than those of control group,the differences were all statistically significant(P<0.05).Pearson correlation analysis showed the serum PCT,NLR and CD8^+were positively correlated with prognosis of patients with sepsis(P<0.05),the peripheral blood T lymphocyte subsets indexes were negatively correlated with prognosis of patients with sepsis(P<0.05).Conclusion:The serum PCT,NLR and peripheral blood T lymphocyte subsets of patients with sepsis show all abnormal expression state,and they have close relationship to the prognosis of these patients,so the detection value of these indexes in the patients with sepsis are higher.
作者
黄葵好
覃莎
HUANG Kuihao;QIN Sha(Foshan Chancheng District Central Hospital,Foshan 528000,China)
出处
《中国医学创新》
CAS
2019年第20期37-40,共4页
Medical Innovation of China
基金
佛山市自筹经费科技计划项目(2018AB003351)
