摘要
GBZ 97-2017《职业性放射性肿瘤判断规范》领衔起草单位——中国医学科学院放射医学研究所研发了其配套的计算机软件。笔者主要介绍了该软件的计算逻辑,即GBZ 97- 2017的病因概率估算的方法学,包括病因概率可进行病因判断的理论基础、辐射致癌危险模型及其中国化的人群间危险模型、使用吸烟校正因子剔除肺癌的吸烟归因份额、使用剂量和剂量率校正因子估算低剂量照射危险和使用潜伏期校正因子校正肿瘤潜伏期内照射危险,以及GBZ 97-2017配套软件研发的概况及不足之处,并建议开发网络版软件。
As the leading institute of the draft group, the Institute of Radiation Medicine, Chinese Academy of Medical Sciences drafted "Judgment standard for occupational radiogenic neoplasms" GBZ 97-2017 and developed its software. This paper introduces the calculation logic of the software, as follow: the methodology of probability of causation in GBZ 97-2017, including the theoretical basis of rationality for using causation probability for the judgment of radiogenic neoplasms;Japanese risk model in estimating cancer risks induced by ionizing radiation and risk transfer model from Japanese population to Chinese population;and use of smoking correction factors to eliminate smoking attribution to lung cancer. This paper introduces the general situation of GBZ 97- 2017 software development and its deficiencies and suggests the development of an online software.
作者
孙志娟
刘强
涂文军
王芹
王津晗
王彦
杜利清
徐畅
王继先
Sun Zhijuan;Liu Qiang;Tu Wenjun;Wang Qin;Wang Jinhan;Wang Yan;Du Liqing;Xu Chang;Wang Jixian(Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine,Institute of Radiation Medicine,Chinese Academy of Medical Sciences,Tianjin 300192,China)
出处
《国际放射医学核医学杂志》
2019年第3期285-290,共6页
International Journal of Radiation Medicine and Nuclear Medicine
基金
国家自然科学基金(81502760、31670859)
天津市自然科学基金(18JCYBJC26800、18JCQNJC12300)
中国博士后科学基金(2018M630106)
中国医学科学院医学与健康科技创新工程项目(2019-I2M-2-006、2017-I2M-1-016)
协和小规模特色办学经费(10023201601602).
关键词
职业性放射性肿瘤
病因概率方法学
国家职业卫生标准
计算机软件
Occupational radiogenic neoplasms
Methodology of probability of causation
National occupational health standards
Computer software
