摘要
目的:研究瑶族保健酒方的抗疲劳作用。方法:将KM种小鼠随机分为对照组(生理盐水)、红景天组[0.39g(kg·d)]、瑶医保健酒方高剂量组[54.29g(kg·d)]、中剂量组[27.14g(kg·d)]、低剂量组[13.57g(kg·d)]5组。各组分别给予等容积不同药物连续灌胃30d后,观察测定小鼠负重游泳力竭时间、小鼠运动后血清尿素含量、血乳酸含量、肝糖原含量,以及小鼠实验前后体质量的变化。结果:各组小鼠实验前、灌胃15、30d体质量比较,差异无统计学意义(P>0.05);瑶族保健酒方中剂量组、红景天组小鼠负重游泳时间均明显长于对照组、瑶族保健酒方高、低剂量组(P<0.05);瑶族保健酒方高剂量组、红景天组均能降低小鼠运动后的血清尿素氮、血乳酸含量(P<0.05);瑶族保健酒方高、中剂量组、红景天组均能提高运动后小鼠肝糖原含量(P<0.01或P<0.05)。结论:瑶族保健酒方具有明显的抗疲劳作用。
Objective:To study the anti-fatigue effect of Yao ethnic health wine.Methods:KM mice were randomly divided into control group(normal saline),Rhodiola group[0.39 g/(kg·d)],Yao medical health wine high-dose group[54.29 g/(kg·d)],middle-dose group[27.14 g/(kg·d)]and low-dose group[13.57 g/(kg·d)].Each group was given equal volume of different drugs for 30 days.The time of exhaustion of weight-bearing swimming mice,serum urea content after exercise,blood lactate content,hepatic glycogen content,and body weight changes were observed and measured.Results:There was no significant difference in the body weight between the mice in each group before and after 15 and 30 days(P>0.05).The swimming time of weight-bearing in the Yao middle-dose group and the Rhodiola group was significantly longer than that of the control group,Yao high-dose group and Yao low-dose group(P<0.05);Yao high-dose group and Rhodiola group can reduce serum urea nitrogen and blood lactate content after exercise in mice(P<0.05);Yao high-dose group,Yao middle-dose group and Rhodiola group can improve the liver glycogen content of mice after exercise(P<0.01 or P<0.05).Conclusion:Yao health wine has obvious anti-fatigue effect.
作者
马建泽
李彤
马艳
刘莉
许莉
MA Jian-ze;LI Tong;MA Yan;LIU Li;XU Li(Yao Medical College,Guangxi University of Traditional Chinese Medicine,Nanning Guangxi 530001,China)
出处
《中医药导报》
2019年第9期55-57,64,共4页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
广西壮瑶医药与医养结合人才小高地项目(中共广西区委办公厅发[2017]44号,NO:QT17011)
关键词
瑶医“盈亏平衡”理论
保健酒
抗疲劳
小鼠
Yao medical's theory of"break-even"
health wine
anti-fatigue
mice
