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不同抗结核治疗方案对慢性乙肝合并肺结核的疗效及肝损伤作用对比 被引量:3

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摘要 目的:比较在慢性乙肝合并肺结核患者治疗中应用两种不同抗结核治疗方案的效果及肝损伤情况。方法:选取医院收治的慢性乙肝合并肺结核患者90例,以随机数字表将患者分为A组(45例)和B组(45例),分别予以2HRZE/4HR方案和3HELLfx/3HELfx方案治疗,同时予以保肝和抗乙肝病毒治疗。对比治疗前后两组的肝功能指标变化,并对比两组的治疗效果。结果:治疗后两组的天门冬氨酸转移酶(AST)、丙氨酸氨基转移酶(ALT)、总胆红素(TBIL)均升高(P<0.05),B组低于A组(P<0.05),两组治疗后的白蛋白(ALB)均下降(P<0.05),B组高于A组(P<0.05);B组的治疗有效率高于A组(P<0.05)。结论:在慢性乙肝合并肺结核患者中应用3HELLfx/3HELfx抗结核方案对肝功能的损伤小于2HRZE/4HR方案,并可获得更好的治疗效果。
作者 刘琼
出处 《医学理论与实践》 2019年第11期1690-1692,共3页 The Journal of Medical Theory and Practice
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