摘要
目的对肺结核患者采用左氧氟沙星联合抗结核方案探讨其临床效果。方法将2017年1月至2020年12月在我院接受治疗的30例肺结核患者随机分为两组,每组15例,对照组接受常规抗结核方案治疗,观察组接受常规抗结核方案+左氧氟沙星治疗,比较两组治疗效果。结果观察组的治疗总有效率93.33%,对照组的治疗总有效率为80.00%,相较于对照组,观察组的治疗总有效率更高(P<0.05);在患者接受治疗前,两组的生活质量并没有明显差异(P>0.05);经过治疗后,相较于对照组,观察组的生活质量各维度评分更具有优势(P<0.05);相较于对照组,观察组的不良反应发生率更低(P<0.05)。结论对肺结核患者采用左氧氟沙星联合抗结核方案治疗效果显著,可提高患者的生活质量,减少不良反应的发生,具有较高安全性,值得在临床上推广应用。
Objective To investigate the clinical effect of levofloxacin combined with antituberculosis in non tuberculosis patients. Methods Thirty patients with pulmonary tuberculosis in our hospital from January 2017 to December 2020 were randomly divided into two groups, 15 cases in each group. The control group was treated with conventional anti tuberculosis regimen, and the observation group was treated with conventional anti tuberculosis regimen + levofloxacin, and compared the two groups’ treatment effect. Results The total effective rate of the observation group was 93.33%, and that of the control group was 80.00%. Compared with the control group, the total effective rate of the observation group was higher, and the difference between the two groups was significant(P<0.05). Before the treatment, there was no significant difference in the quality of life between the two groups(P>0.05). After treatment, compared with the control group, the score of each dimension of the quality of life in the observation group was higher(P<0.05). Compared with the control group, the incidence of adverse reactions in the observation group was lower, and the difference was significant(P<0.05). Conclusion The effect of levofloxacin combined with antituberculosis in the treatment of patients with pulmonary tuberculosis is significant, which can improve the quality of life of patients, reduce the occurrence of adverse reactions, has high safety, and is worthy of clinical application.
作者
杨新建
YANG Xin-jian(The First People's Hospital of Guannan County,Lianyungang,Jiangsu 222500)
出处
《智慧健康》
2021年第17期163-165,共3页
Smart Healthcare
关键词
左氧氟沙星
抗结核方案
临床效果
安全性
Levofloxacin
Anti tuberculosis program
Clinical effect
Safety
