摘要
目的探究血府逐瘀汤加减治疗老年女性失眠的临床效果,并分析其对生活质量的影响。方法选取2016年3月—2018年7月收治的老年女性失眠患者126例,将其分为对照组(63例)和观察组(63例),对照组给予西医治疗,观察组在此基础上给予血府逐瘀汤加减治疗,2组连续治疗4周,统计2组治疗后临床疗效和激素指标的差异,观察2组治疗前后睡眠质量和生活质量的变化。结果治疗后观察组与对照组的临床总有效率分别为95. 24%、79. 37%,观察组显著高于对照组(P <0. 05);与治疗前比,治疗后2组性激素指标和匹兹堡睡眠质量指数(PSQI)均显著下降(P <0. 05),治疗后观察组以上指标比对照组明显降低(P <0. 05)。与治疗前比,治疗后2组WHOQOL-BREF总分显著升高,且观察组显著高于对照组(P <0. 05)。结论血府逐瘀汤加减治疗可有效缓解老年女性失眠患者临床症状,改善性激素指标,保障老年女性的正常睡眠,提高生活质量,且疗效优于西医治疗,值得临床推广应用。
Objective To explore the clinical effect of Xuefu Zhuyu decoction on insomnia in elderly women,and to analyze its impact on the quality of life.Methods 126 elderly female insomniacs admitted to our hospital from March 2016 to July 2018 were divided into control group(n=63)and observation group(n=63).The control group was treated with Western medicine,while the observation group was treated with Xuefu Zhuyu decoction on the basis of this treatment.The two groups were treated for 4 weeks continuously.The differences of clinical efficacy and hormone indexes between the two groups were counted,and the sleep quality of the two groups before and after treatment and changes in quality of life was observed.Results After treatment,the total clinical effective rates of the observation group and the control group were 95.24%and 79.37%,respectively.The total clinical effective rate of the observation group was significantly higher than that of the control group(P<0.05).Compared with before treatment,the sex hormone index and Pittsburgh Sleep Quality Index(PSQI)of the two groups were significantly decreased after treatment(P<0.05).After treatment,the above indexes of the observation group were significantly lower than that of the control group(P<0.05).Compared with before treatment,the total score of WHOQOL-BREF in the two groups increased significantly after treatment,and the total score of WHOQOL-BREF of the observation group was significantly higher than that of the control group(P<0.05).Conclusion The modified Xuefu Zhuyu decoction can effectively alleviate the clinical symptoms of elderly women with insomnia,improve the sex hormone indicators,ensure the normal sleep of elderly women,improve the quality of life,and the curative effect is better than that of Western medicine,which is worthy of clinical application.
作者
卢茂华
LU Maohua(Department of TCM Internal Medicine,Jiamusi Hospital of Traditional Chinese Medicine,Heilongjiang Province,Jiamusi 154002,China)
出处
《光明中医》
2019年第9期1323-1325,共3页
GUANGMING JOURNAL OF CHINESE MEDICINE
关键词
血府逐瘀汤
老年女性
失眠症
生活质量
中西医结合疗法
Xuefu Zhuyu decoction
elderly women
insomnia
Quality of life
therapy of integrated medicine