摘要
《中国药典》2010年以后版本均以木通科木通(五叶木通)Akebia quinata(Thunb.)Decne.,三叶木通Akebia trifoliata(Thunb.)Koidz.或白木通Akebia trifoliata(Thunb.)Koidz.Var australis(Diels)Rehd为抗癌中药预知子来源。同源藤茎入药之木通始载于《神农本草经》,又名通草,但《本草纲目》中除收载通草子(木通科种子,又名燕覆子)外,另收载了"预知子",可见二者非同一基源。然正是由于有通草之名,导致长期与毛茛科铁线莲属川木通、马兜铃科关木通混用。直到关木通导致肾毒事件之后,2015版药典才将其区别。因此,建议现中国药典之预知子的学名改为"燕覆(Akebiae Fructus)"。并将木通严格区别于关木通和川木通。其在资源分布上,预知子/燕覆广泛分布于长江及黄河流域各省、东南地区及台湾。日本、朝鲜、俄罗斯亦有分布报道。但重庆、福建未见有野生资源报道。重庆自1997年行政区划方独立于四川成立直辖市,其周边湖北、湖南、陕西、贵州地区均有三叶木通、白木通分布;而福建周边浙江、江西、广东、台湾均有白木通分布,鉴于四川省为木通药材资源分布地区。因此,推测重庆应有三叶木通、白木通分布;福建应有白木通分布,有待今后进一步去证实。
The Chinese Pharmacopoeia version after 2010 is Akebia quinata(Thunb.)Decne.,Akebia trifoliata(Thunb.)Koidz.or Akebia trifoliata(Thunb.)Koidz Var australis(Diels)Rehd is a predictor of anticancer traditional Chinese medicine.The root of the homologous cane is contained in the"Shen Nong’s Herbal Classic",also known as the grass,but in the"Compendium of Materia Medica",in addition to carrying the grass(Mu Tongke seeds,also known as Yanzizi),another collection"Predicting the child"shows that the two are not the same base.However,it is precisely because of the name of the grass,resulting in long-term mixed with the Ranunculaceae Clematis Chuanmutong,Aristolochia Branch.The 2015 edition of the Pharmacopoeia differentiated it until after Guan Mutong caused a kidney poisoning event.Therefore,it is recommended that the scientific name of the pre-existing child of the Chinese Pharmacopoeia be changed to"Akebiae Fructus".And Mutong is strictly different from Guanmutong and Chuanmutong.In termsof resource distribution,the pre-knowledge/yan cover is widely distributed in the provinces of the Yangtze and Yellow River basins,the southeastern region,and Taiwan.Japan,North Korea,and Russia also have reports.However,there are no reports of wild resources in Chongqing and Fujian.Chongqing has established a municipality directly under the jurisdiction of Sichuan since 1997.Its surrounding Hubei,Hunan,Shaanxi,and Guizhou regions have distribution of Sanye Mutong and Baimutong.In Zhejiang,Zhejiang,Jiangxi,Guangdong,and Taiwan,there are Baimutong distributions.The province is the distribution area of Mutong medicine resources.Therefore,it is speculated that Chongqing should have the distribution of Sanye Mutong and Baimutong;Fujian should have Baimutong distribution,which needs further confirmation in the future.
作者
周莉
李琛
曹风军
李洪亮
汪选斌
ZHOU Li;LI Chen;CAO Fengjun;LI Hongliang;WANG Xuanbin(Laboratory of Chinese Herbal Pharmacology Oncology Center of Affiliated Hospital of Hubei University of Medicine,Hubei Shiyan 442000,China;Hubei Key Laboratory of Wudang Local Chinese Medicine Research,Hubei Shiyan 442000,China;Biomedical Research Institute of Hubei University of Medicine,Hubei Shiyan 442000,China)
出处
《中医药临床杂志》
2019年第5期799-803,共5页
Clinical Journal of Traditional Chinese Medicine
基金
国家自然基金面上项目(81874356)
湖北省卫计委重点项目(WJ2017Z023)
湖北省高等学校优秀中青年科技创新团队计划(T201510)
湖北省教育厅科学技术研究项目(B2014046
B2015471)
湖北医药学院优秀中青年团队项目(2014CXG03)
湖北医药学院自由探索基金项目(YHXT01)
湖北省学科建设项目
湖北医药学院重点学科建设经费资助(2014XKJSXJ18)
关键词
预知子
燕覆
本草考证
资源分布
Akebiae Fructus
Yanfu
Textual research
Resource distribution
