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甲醛危害性工程学评价模型的实验研究 被引量:1

A Study of Engineering Risk Evaluation Model for the Superposition of Formaldehyde based on Drosophila’s Life-cycle
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摘要 本文主要研究在国标限量浓度上下的低浓度甲醛对果蝇的影响,同时建立其危害性工程学评价模型。实验以Oregon K野生型黑腹果蝇为实验对象,以果蝇的半数死亡天龄(LT50)作为评价标准,使其暴露在动态浓度稳定控制的染毒装置中,污染物浓度控制在0~900μg/m^3范围内。实验结果表明,果蝇的半数死亡天龄与甲醛浓度间存在明显负相关性(相关性r=-0.980,显著性P<0.01)。在同等暴露浓度下,雌性果蝇对甲醛浓度耐受性较雄性果蝇弱,半数死亡天龄小于雄性果蝇。根据甲醛的剂量与果蝇寿命的关系,建立了甲醛浓度与危害性指数(HI)之间的Logistic回归模型(拟合度R^2=0.996)。 This paper mainly studies the effects of formaldehyde on drosophila at low concentration which close to national standards and establishes a corresponding risk evaluation model. The experiment exposed drosophila in a dynamic exposure equipment which used Oregon K wildtype drosophila’s median lethal time (LT50) as evaluation standard. The formaldehyde concentration was controlled at 0-900μg /m^3 . The experiment result showed an obvious negative correlation between drosophila’s median lethal time and formaldehyde concentration (r=0.980, P<0.01). During the experiment female drosophila’s median lethal time was shorter than male at the same concentration which showed a sexual difference. According to the doseresponse relationship of formaldehyde, a logistic regression model between formaldehyde hazard index (HI) and concentration was established (R^2= 0.996).
作者 逯浩圻 李振海 秦郭骏 LU Haoqi;LI Zhenhai;QIN Guojun(School of Mechanical Engineering, Tongji University)
出处 《建筑热能通风空调》 2019年第3期32-35,共4页 Building Energy & Environment
关键词 甲醛 果蝇 半数死亡天龄 LOGISTIC回归模型 Formaldehyde drosophila exposure experiment median lethal time (LT50) logistic regression
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