摘要
目的:观察半夏白术天麻汤加减治疗急性脑梗死的临床疗效。方法:将90例急性脑梗死患者按照随机数字表法分为观察组和对照组,每组各45例。对照组给予依达拉奉注射液+银杏达莫注射液治疗,观察组在对照组的基础上加用半夏白术天麻汤治疗。观察两组患者的临床疗效,比较两组患者治疗前后中医证候积分、神经功能缺损程度评分(NIH-SS)、Barthel指数(BI)评分变化情况;检测两组患者治疗前后全血高切黏度、全血低切黏度、血浆黏度、红细胞压积(hem-atocrit,HCT)、纤维蛋白原(fibrinogen,FIB)水平。结果:对照组有效率为82. 22%,观察组有效率为95. 56%,两组患者临床疗效比较,差异具有统计学意义(P <0. 05)。两组患者治疗后中医证候积分低于本组治疗前,且观察组治疗后低于对照组,差异具有统计学意义(P <0. 05)。两组患者治疗后NIHSS评分低于本组治疗前,BI评分高于本组治疗前,观察组治疗后NIHSS评分低于对照组,BI评分高于对照组,差异均有统计学意义(P <0. 05)。观察组治疗结束后全血高切黏度、全血低切黏度、血浆黏度、HCT、FIB水平低于对照组,差异具有统计学意义(P <0. 05)。结论:半夏白术天麻汤加减治疗急性脑梗死可明显改善患者神经功能和血液流变学指标。
Objective:To observe the clinical curative effect of Modified Pinellia and White Atractylodes and Gastrodia Decoction in combination with Edaravone Injection on acute cerebral infarction.Methods:Ninety patients with acute cerebral infarction were divided into the observation group and the control group according to the random number table method,with 45 cases in each group.The ones in the control group were treated with Edaravone Injection together with Ginkgo Leaf Extract and Dipyridamole Injection,while the ones in the observation group were treated with Pinellia and White Atractylodes and Gastrodia Decoction on the basis of the control group.The clinical efficacies of the two groups were observed.The TCM syndrome scores,neurological deficit scores(NIHSS)and Barthel index(BI)scores before and after the treatment were compared between the two groups.The high blood viscosity,the whole blood low-cut viscosity,plasma viscosity,hematocrit(HCT),fibrinogen(FIB)levels of the two groups before and after treatment were measured.Results:The effective rate of the control group was 82.22%,and that of the observation group was 95.56%.The clinical efficacy of the two groups was statistically significant(P<0.05).The scores of TCM syndromes in the two groups were lower than those in the group before the treatment,and the observation group was lower than the control group after the treatment.The difference was statistically significant(P<0.05).The NIHSS scores of the two groups were lower than those of the group before the treatment,and the BI score was higher than that of the group before the treatment.The NIHSS score of the observation group was lower than that of the control group,and the BI score was higher than that of the control group.The differences were statistically significant(P<0.05).The high blood viscosity,whole blood low-cut viscosity,plasma viscosity,HCT and FIB levels of the observation group were lower than those of the control group after treatment,and all the differences were statistically significant(P<0.05)
作者
景小莉
JING Xiao-li(Xinmi First People's Hospital,Xinrni,Henan,China,452370)
出处
《河南中医》
2019年第1期74-77,共4页
Henan Traditional Chinese Medicine
关键词
急性脑梗死
半夏白术天麻汤
依达拉奉注射液
银杏达莫注射液
acute cerebral infarction
Modified Pinellia and White Atractylodes and Gastrodia Decoction
Edaravone Injection
Ginkgo Leaf Extract and Dipyridamole Injection
