摘要
目的:探究百令胶囊与呼吸康复训练联合治疗慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Diseases,COPD)患者的临床效果、血气指标及肺功能的影响。方法:COPD患者212例,按数字表法随机分为对照组(n=104)与观察组(n=108)。两组患者入院后均给予常规药物治疗,包括祛痰、控制感染、解痉平喘等,在此基础上,予以对照组百令胶囊进行治疗,而观察组采用百令胶囊联合呼吸康复训练进行治疗,分析两组患者肺功能情况、各项血气分析指标、6MWD、生存质量及临床总有效率。结果:经过治疗后,观察组FEV_1(2.12±0.89)L、FVC(2.55±0.82)L、FEV_1/FVC(80.69±10.32)%、FEV(42.38±6.42)%等均明显高于对照组FEV_1(1.87±0.85)L、FVC(2.33±0.84)L、FEV_1/FVC(76.27±7.65)%、FEV(38.17±4.23)%;经治疗1～3个月,两组患者的6MWD均呈上升趋势,且治疗后1～3个月观察组的6MWD值均明显高于对照组;观察组PaO_2(70.21±5.27)mmHg、SaO_2(88.96±4.19)mmHg值均明显高于对照组PaO_2(65.29±5.14)mmHg、SaO_2(84.25±4.62)mmHg值,观察组PaCO_2(40.05±3.11)mmHg明显低于对照组的(43.28±6.43);观察组整体生存质量均明显优于对照组;观察组临床总有效率(92.59%)明显高于对照组的(71.15%),差异均有统计学意义(P<0.05)。结论:COPD患者在常规治疗基础上加用百令胶囊联合呼吸康复训练治疗后,患者肺通气换气功能有了显著改善,呼吸困难等不适症状得到有效缓解,整体治疗效果较优。
Objective:To explore the effect of Bailing Capsule combined with respiratory rehabilitation training on the clinical effect,blood gas index and pulmonary function of the patients with chronic obstructive pulmonary disease(COPD).Methods:Totally 212 cases of COPD were selected and randomly divided into the control group(n=104)and the observation group(n=108)according to the number table method.The two groups of patients were given routine drug treatment,including infection control,expectorant,antispasmodic drugs.On this basis the control group was given Bailing Capsule treatment and the observation group were given Bailing Capsule combined with respiratory rehabilitation training treatment.The two groups’pulmonary function and the blood gas analysis index,6 MWD,survival quality and clinical total efficiency were compared.Results:After treatment,the observation group’s FEV1(2.12±0.89)L,FVC(2.55±0.82)L,FEV1/FVC(80.69±10.32)%,and FEV(42.38±6.42)%were significantly higher than the control group’s FEV1(1.87±0.85)L,FVC(2.33±0.84)L,FEV1/FVC(76.27±7.65)%and FEV(38.17±4.23)%.After 1~3 months treatment,two groups’6 MWD showed an upward trend,and after 1~3 months treatment the observation group’s 6 MWD values were significantly higher than the control group’s.The observation group’s PaO2(70.21±5.27)mmHg and SaO2(88.96±4.19)mmHg were significantly higher than the control group’s PaO2(65.29±5.14)mmHg and SaO2(84.25±4.62)mmHg.The observation group’s PaCO2(40.05±3.11)mmHg was significantly lower than the control group’s(43.28±6.43)mmHg.The observation group’s overall quality of life was significantly better than that of the control group.The total efficiency of the observation group(92.59%)was significantly higher than the control group’s(71.15%),and the difference was statistically significant(P<0.05).Conclusion:On the basis of routine treatment,adding Bailing Capsule combined with respiratory rehabilitation training for the patients with chronic obstructive pulmonary disease can significant
作者
楼滟
王晓宇
张鹏
方金菊
叶珺
LOU Yan;WANG Xiaoyu;ZHANG Peng;FANG Jinju;YE Jun(Department of Respiration,Hangzhou Hospital of Zhejiang Medical and Health Group,Hangzhou 310022,Zhejiang,China;Zhejiang Provincial Cancer Hospital,Hangzhou 310017,Zhejiang,China)
出处
《中华中医药学刊》
CAS
北大核心
2019年第2期421-424,共4页
Chinese Archives of Traditional Chinese Medicine
基金
浙江省卫生医药科技项目一般研究项目A类(2015KYA039)
关键词
肺功能
百令胶囊
血气指标
呼吸康复训练
lung function
Bailing Capsule
blood gas index
respiratory rehabilitation training
