摘要
胃癌在我国恶性肿瘤中的发病率和死亡率均较高。幽门螺杆菌(Hp)感染在胃黏膜炎症、萎缩和肠化生中起重要作用,大量流行病学研究证据显示,Hp感染与胃癌发病呈正相关。目前,我国人群Hp现症感染率接近50%,根除Hp可降低胃癌发生风险,并具有成本效果优势,但筛查并根除Hp在我国应用并不广泛。本文从卫生经济学角度阐述Hp筛查与根除在胃癌预防中的作用,并分析影响这一决策实施的关键因素。
The morbidity and mortality of gastric cancer are very high in China. Helicobacter pylori (Hp) infection plays an important role in gastric mucosa inflammation, atrophy and intestinal metaplasia. A large number of epidemiological researches have shown a positive correlation between Hp infection and morbidity of gastric cancer. The current infection rate of Hp in China is nearly 50%. Eradication of Hp may reduce the risk of gastric cancer and bring a better cost-effectiveness. However, screening and eradication of Hp had not been taken seriously in China. This article analyzed the effectiveness and affecting factors of screening and eradication of Hp for gastric cancer prevention from the health economics perspective view.
作者
蒋颖溢
黄晓铨
陈世耀
JIANG Yingyi;HUANG Xiaoquan;CHEN Shiyao(Department of Gastroenterology and Hepatology,Zhongshan Hospital,Fudan University,Evidence-based Medicine Center,Shanghai 200032)
出处
《胃肠病学》
2019年第2期65-70,共6页
Chinese Journal of Gastroenterology
基金
上海市第四轮公共卫生三年行动计划重点学科建设项目"循证公共卫生与卫生经济学"(15GWZK0901)
关键词
胃肿瘤
幽门螺杆菌
筛查
根除治疗
决策
卫生经济学
Stomach Neoplasms
Helicobacter pylori
Screening
Eradication
Decision Making
Health Economics
