摘要
目的:通过分析外周血高密度脂蛋白(high density lipoprotein,HDL)与乳腺癌患者术后切口愈合情况的相关性,探讨HDL对切口愈合的影响。方法:收集在汕头大学医学院第二附属医院行乳腺癌手术的住院患者132例;于术前进行HDL检测,术后统计引流管留置天数、引流量、换药次数及拆线时间作为切口愈合指标,并进行相关性分析。结果:HDL高于正常组引流管留置天数、引流量、换药次数及拆线时间等指标与HDL正常组、HDL低于正常组相比差异有统计学意义(均P <0.01);HDL水平与各愈合指标均呈显著负相关,其中与引流量相关性最高(r=-0.36,P <0.01)。结论:高水平的HDL对促进乳腺癌切口愈合或起到重要作用。
Objective:To investigate the effect of HDL on wound healing by analyzing the correlation between peripheral blood HDL and postoperative incision healing in patients with breast cancer.Methods:A total of 132 inpatients who underwent breast cancer surgery in the Second Affiliated Hospital of Shantou University Medical College were enrolled.HDL was detected before surgery.Drainage tube retention time,drainage volume,number of dressings and time of suture removal were counted and as an indicator of wound healing and conduct correlation analysis.Results:The group which have a higher HDL have a lower drainage tube retention time(P<0.01),drainage volume(P<0.01),dressing frequency(P<0.01)and suture removal time(P<0.01)than the normal or lower HDL level group;HDL levels were significantly negatively correlated with each healing index,and the correlation with drainage was the highest(r=-0.36,P<0.01).Conclusion:High level of HDL plays an important role in promoting breast cancer incision healing.
作者
郑杰华
王薇
柯创滨
林晓琪
陈业晞
ZHENG Jiehua;WANGWei;KE Chuangbin;LIN Xiaoqi;CHEN Yexi(Department of Surgery,The Second Affiliated Hospital of Shantou University Medical College,Shantou 515041,China)
出处
《汕头大学医学院学报》
2019年第1期18-20,共3页
Journal of Shantou University Medical College
