摘要
目的研究18F-FDGPET-CT与胸部屏气螺旋CT联合在非小细胞肺癌(NSCLC)术前TNM分期诊断中的应用价值。方法将我院收治62例NSCLC患者纳为研究对象,以病理检查结果作为"金标准",评估18F-FDGPET-CT与胸部屏气螺旋CT在NSCLC术前分期中的应用价值。结果 62例患者中,CT-T分期准确性为80.65%(50/62),18F-FDGPET/CT-T分期准确性为64.52%(40/62),两组T分期准确率显著性差异(P<0.05);中央型肺癌伴明显阻塞性改变患者CT-T分期准确率为14.29%(1/7),18F-FDGPET/CT-T分期准确率为71.43%(5/7),两组诊断正确率差异显著(P<0.05);CT密度法-N分期准确率为67.84%,摄取法-N分期准确率为69.35%,CT密度+摄取法-N分期准确率为77.42%,三组N分期准确率无显著性差异(P>0.05);CT-M分期准确率为91.94%,18F-FDGPET/CT-M分期准确率为98.39%,两组M分期准确度无显著性差异(P>0.05);CT-TNM分期准确性为80.65%,18F-FDGPET/CT+CT-TNM分期准确性为91.94%,两组TNM分期准确性无显著性差异(P>0.05)。结论 CT联合18F-FDG PET/CT可有效提高NSCLC患者术前分期准确率。
Objective To study the application value of 18F-FDG PET-CT combined with chest breath-hold spiral CT in the diagnosis of preoperative TNM staging of non-small cell lung cancer(NSCLC).Methods A total of 62 cases of patients with NSCLC admitted to our hospital were selected for the study.The results of pathological examination were used as the gold standard to evaluate the application value of 18F-FDG PET-CT and chest breath-hold spiral CT in preoperative staging of NSCLC.Results Among the 62 patients,the accuracy of CT-T staging was 80.65%(50/62),and the accuracy of 18F-FDG PET/CT-T staging was 64.52%(40/62),and there was a significant difference in the accuracy of T staging between the two groups(P<0.05).The accuracy of CT-T staging was 14.29%(1/7)in patients with central lung cancer and obvious obstructive changes,and the accuracy of 18F-FDG PET/CT-T staging was 71.43%(5/7),and the difference in correct diagnosis rate was significant between the two groups(P<0.05).The accuracy of CT density-N staging was 67.84%,and the accuracy of uptake-N staging was 69.35%,and the accuracy of CT density and uptake-N staging was 77.42%,and there was no significant difference in the accuracy of N staging among the groups(P>0.05).The accuracy of CT-M staging was 91.94%,and the accuracy of 18F-FDG PET/CT-M staging was 98.39%,and there was no significant difference in the accuracy of M staging between the two groups(P>0.05).The accuracy of CT-TNM staging was 80.65%,and the accuracy of 18F-FDG PET/CT+CT-TNM staging was 91.94%,and there was no significant difference in accuracy of TNM staging between the two groups(P>0.05).Conclusion CT and 18 F-FDG PET/CT can effectively improve the accuracy of preoperative staging of patients with NSCLC.
作者
王总飞
李鹏
杨慧远
刘先本
张瑞祥
刘士磊
WANG Zong-fei;LI Peng;YANG Hui-yuan(Department of Thoracic Surgery,Cancer Hospital Affiliated to Zhengzhou University,Zhenzhou 450008,Henan Province,China)
出处
《中国CT和MRI杂志》
2018年第12期75-77,118,共4页
Chinese Journal of CT and MRI
基金
河南省科技攻关项目(132201110029)
