摘要
目的探讨抗生素骨水泥与抗生素持续灌注冲洗治疗骨折术后髓内感染的疗效。方法选取我院2016年2月～2017年6月52例骨折术后髓内感染患者,数字随机抽取分成观察组与对照组,对照组采用抗生素持续灌注冲洗治疗,观察组采用抗生素骨水泥治疗,对比两组手术情况、疼痛情况(VAS评分)及血沉(ESR)、C反应蛋白(CRP)、白细胞、中性粒细胞变化。结果观察组术后出血量少于对照组,观察组伤口愈合时间、下床活动时间、住院时间均短于对照组(P<0.05);观察组术后6 h、12 h VAS评分均低于对照组(P<0.05);观察组治疗后2周ESR、CRP、白细胞、中性粒细胞水平均低于对照组(P<0.05)。结论抗生素骨水泥与抗生素持续灌注冲洗治疗骨折术后髓内感染均具有明显效果,抗生素骨水泥可缓解疼痛,控制感染,促进患者康复,具有更高的应用价值。
Objective To compare the efficacy of antibiotic bone cement and antibiotic continuous perfusion in the treatment of intramedullary infection after fracture.Methods52patients with intramedullary infection after fracture in our hospital from February2016to June2017were randomly divided into observation group and control group.The control group was treated with antibiotic continuous perfusion and the observation group was treated with antibiotic bone cement.The surgery,pain(VAS score)and erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),white blood cells,neutrophil changes between the two groups of surgery were compared.Results The amount of postoperative bleeding in the observation group was lower than that in the control group.The wound healing time,the time of getting out of bed,and the hospitalization time were shorter in the observation group than those in the control group(P<0.05).The VAS scores in the observation group were lower than those in the control group at6h and12h after operation(P<0.05).ESR,CRP,white blood cell and neutrophil levels were lower in the observation group than those in the control group at2weeks after treatment(P<0.05).Conclusion Antibiotic bone cement and antibiotic continuous perfusion washing have obvious effects on intramedullary infection after fracture.Antibiotic bone cement can relieve pain,control infection and promote rehabilitation of patients.It has higher application value.
作者
潘小明
PAN Xiaoming(Department of Orthopaedics,Yichun Zhegan Friendship Hospital in Jiangxi Province,Yichun 336000,China)
出处
《中国现代医生》
2018年第32期99-101,106,共4页
China Modern Doctor
关键词
抗生素骨水泥
抗生素持续灌注冲洗
骨折
髓内感染
Antibiotic bone cement
Antibiotic continuous perfusion
Fracture
Intramedullary infection
