摘要
目的:探讨小儿重型ITP治疗中单次大剂量丙种球蛋白的临床疗效。方法:收治小儿重症ITP患者60例,随机分为两组。对照组给予常规剂量丙种球蛋白治疗,观察组给予大剂量丙种球蛋白治疗,比较两组临床症状控制率、不良反应发生率。结果:观察组血液指标改善时间短于对照组,症状控制率高于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:小儿重型ITP治疗中单次大剂量丙种球蛋白的应用能够提升患者的整体治疗效果。
Objective:To investigate the clinical effect of single large dose of gamma globulin in the treatment of children with severe ITP.Methods:60 cases of children with severe ITP were divided into two groups randomly.The control group was treated with routine dose of gamma globulin,and the observation group was treated with large dose of gamma globulin,the control rate of clinical symptoms and the incidence of adverse reactions were compared between the two groups.Results:The improvement time of blood indexes in the observation group was shorter than that in the control group,and the control rate of clinical symptoms was higher than that in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Single large dose of gamma globulin in the treatment of children with severe ITP could improve the overall treatment effect.
作者
易雪岚
郭秀彬
蒋焰
Yi Xuelan;Guo Xiubin;Jiang Yan(The Second Department of Pediatrics,the Hospital Affiliated to Zunyi Medical College(Guizhou)563000)
出处
《中国社区医师》
2018年第32期67-67,69,共2页
Chinese Community Doctors
关键词
重型ITP
丙种球蛋白
血液指标
临床疗效
Severe immune thrombocytopenia
Gamma globulin
Blood index
Clinical effect