摘要
目的了解住院老年人骨质疏松与器官异位钙化的相关性。方法选取2013年3月~2016年9月在解放军第一八一医院住院的322例老年患者。记录性别、年龄、体重指数、骨密度取股骨或腰椎两个部位的低值,其中,骨量正常组88例,骨量减少组96例,骨质疏松组138例。采用美国生产的DPX-NT双能X骨密度仪,测量部位为L2~L4、双侧股骨颈、粗隆及Wards三角区,用CT或X线片或彩超检查头颅、脊柱、膝关节、肺部、双侧颈动脉、腹主动脉、下肢动脉、肝、胆、肾等。按低龄老年人、高龄老年人及全部老年人、男性、女性的骨密度与上述器官有无钙化进行偏相关分析。结果骨量正常组、骨量减少组、骨质疏松组三组比较:腹主动脉钙化、腰椎压缩性骨折、膝关节退行性变成增生差异有高度统计学意义(P<0.01)。两两比较显示,腹主动脉钙化、膝关节退变或增生,骨质疏松组比骨量减少组及骨量正常组严重(P<0.05);腰椎压缩性骨折,骨量减少组和骨质疏松组较骨量正常组多发,差异有高度统计学意义(P<0.01)。各组胆道结石比较差异无统计学意义(P>0.05)。按年龄进行偏相关分析:各组患者的骨密度与腰椎骨折相关,全部病例组及高龄老年人组的骨密度与腹主动脉钙化、膝关节退行性变或增生及胆道结石相关(P<0.05)。颈动脉、腹主动脉、下肢动脉钙化,与年轻老年人比较,高龄老年人组均较明显(P<0.01),脊柱退行性变和骨质增生、膝关节退行性变和骨质增生高龄老年人组多见(P<0.05),泌尿系结石、胆道结石也以高龄老年人组多发,差异有统计学意义(P<0.05)。按性别进行偏相关分析:男性骨密度均与腹主动脉钙化、膝关节退行性变或增生、胆道结石相关(P<0.05)。女性骨密度与肾脏钙化和胆道结石相关(P<0.05)。结论骨密度与腹主动脉钙化、腰椎压缩性骨折、肾脏钙化、膝关节退行性变或增生及胆�
Objective To invesLigaLe Lhe relaLionship beLween osLeoporosis and ecLopic calcificaLion in elderly inpa-LienLs.Methods Three hundred and LwenLy-Lwo cases of elderly paLienLs hospiLalized in Lhe 181sL HospiLal of PLA from March 2013 Lo SepLember 2016 were selecLed.Gender,age and body mass index(BMI)were recorded.Bone mineral densiLy(BMD)was measured in Lwo siLes of femur and lumbar spine.There were 88 paLienLs of normal bone mass,96 cases of osLeopenia,138 cases of osLeoporosis.Bone mineral densiLy of siLe L2-L4,bilaLeral femoral neck,LrochanLer and Wards Lriangle were measured by Lhe DPX-NT dual-energy X-ray bone mineral densiLy produced in America.Head,spine,knee joinL,Lhe lungs,bilaLeral caroLid arLeries,abdominal aorLa,lower limb arLery,liver,gallbladder,kidney were checked wiLh CT,X-rays or color ulLrasonic.BMD and calcificaLion of Lhe above organs were analyzed by parLial corre-laLion among Lhe elderly,male and female groups.Results Compared in normal bone,osLeopenia and osLeoporosis groups:Lhe differences of abdominal aorLic calcificaLion,lumbar compression fracLure,knee joinL degeneraLion or prolif-eraLion were sLaLisLically significanL(P<0.01).Compared wiLh each oLher:Lhe differences of abdominal aorLic calcifica-Lion,knee joinL degeneraLion or proliferaLion were significanLly severer in osLeoporosis group Lhan Lhose in bone mass reducLion group and bone normal group(P<0.05);Lhe lumbar compression fracLure in bone mass reducLion group or osLeoporosis group was more common Lhan LhaL of nor-mal group,Lhe difference was sLaLisLically significanL(P<0.01).There was no difference in gallsLone among all groups(P>0.05).ParLial correlaLion analysis ac-cording Lo ages:BMD was associaLed wiLh lumbar frac-Lure in all groups.BMD in all paLienLs and elderly group were associaLed wiLh abdominal aorLic calcificaLion,knee joinL degeneraLion or hyperplasia and gallsLone(P<0.05).CalcificaLion in caroLid arLery,abdominal aorLa,lower exLremiLy arLerial,compared wiLh Lhe younger age group,Lhe older age group were more obvious
作者
刘学员
喻智
熊义博
邓泽熙
卢水焕
赵蕾
何杰
唐慧明
LIU Xueyuan;YU Zhi;XIONG Yibo;DENG Zexi;LU Shuihuan;ZHAO Lei;HE Jie;TANG Huiming(Department of Cadre Ward,the 181st Hospital of PLA,Guangxi Zhuang Autonomous Region,Guilin 541002,China;Department of Ultrasonography,the 181st Hospital of PLA,Guangxi Zhuang Autonomous Region,Guilin 541002,China)
出处
《中国医药导报》
CAS
2018年第20期100-104,共5页
China Medical Herald
基金
军队保健专项科研课题(12BJZ14)
广西壮族自治区桂林市科学研究与技术开发计划项目(2016012702-6)
关键词
骨质疏松
异位钙化
骨密度
偏相关分析
老年人
OsLeoporosis
EcLopiccalcificaLion
Bone mineral densiLy
ParLial correlaLion
Elderly
