摘要
克罗恩病(CD)是一种原因不明的慢性非特异性肠道炎性病变,可累及全消化道。近年来,CD的发病率在世界范围内逐步上升,该疾病具有慢性复发性、不可治愈性、致残性等特点,常导致患者出现严重的精神问题。研究表明,伴有抑郁症状的CD患者通常预后较差,部分重度抑郁患者甚至可能出现自杀倾向。而目前国内对于CD患者抑郁产生的危险因素相关研究较少,且地域、种族、环境、生活习惯、治疗方案等差异的存在,导致我国CD患者抑郁产生原因的资料相当欠缺。
Crohn′s disease(CD)is a chronic non-specific intestinal inflammatory disease that can involve the entire digestive tract.It is reported that the incidence of CD has steadily increased in most parts of the world,with chronic recurrent,unsustainable,disabling and other features.Patients with depression associated with CD usually have poor prognosis,some patients with severe depression may have suicidal tendency.At present,there are few studies on the risk factors of depression in patients with CD in China.In addition,because of the differences of regional,ethnic,environmental,living habits and treatment programs,the data of the causes of depression in CD patients are quite deficient in China.
作者
胡宇倩
张梦慈
谷云飞
杨柏霖
陈红锦
HU Yuqian;ZHANG Mengci;GU Yunfei;YANG Bolin;CHEN Hongjin(Department of Anorectal Medicine,the First Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210000,China)
出处
《医学综述》
2018年第4期708-712,共5页
Medical Recapitulate
基金
国家自然科学基金(81673973)
江苏省自然科学基金(BK20161577)
江苏省"十二五"中医药重点学科基金(JS1301)
江苏高校中医学优势学科建设工程项目(035062002003)
