摘要
目的 调查克罗恩病肛瘘(PFCD)病人的焦虑抑郁发病现状,对其发病的影响因素进行分析,从而为临床身心指导提供理论支撑。方法 选取2020年9月至2021年7月南京中医药大学附属医院肛肠外科住院部就诊的PFCD病人197例,收集病人一般资料及临床表现,采用广泛性焦虑障碍量表(GAD-7)、抑郁症筛查量表(PHQ-9)对病人精神进行评估。结果 在197例PFCD病人中,有66例(33.50%)出现焦虑状态,81例(41.12%)出现抑郁状态。合并并发症[OR=2.25,95%CI:(1.20,4.25)]、肛周手术次数≥2次[OR=2.15,95%CI:(1.17,3.96)]是PFCD病人出现抑郁状态的危险因素;合并并发症[OR=2.27,95%CI:(1.19,4.34)]、疾病处于活动期[OR=2.58,95%CI:(1.04,6.42)]是PFCD病人出现焦虑状态的危险因素。结论 克罗恩病(CD)病人合并肛周瘘管病变发生率高,病程长,治疗难度大,病人由于全身条件和肛周病变往往存在情绪压力,在临床治疗疾病的同时应该关注病人的心理健康。
Objective To investigate the current status of anxiety and depression onset in patients with perianal fistulizing Crohn’s disease(PFCD) and to analyze its influencing factors to provide theoretical support for clinical physical and mental guidance.Methods A total of 197 patients with PFCD in the inpatient department of the Department of Jiangsu Traditional Chinese Medicine Hospital were selected.The general data and clinical manifestations of the patients from September 2020 to July 2021 were collected,their general data and clinical manifestations were collected,and their psychiatric assessment was performed using the Generalized Anxiety Disorder Scale(GAD-7) and the Depression Screening Inventory(PHQ-9).Results Among 197 patients with PFCD,66(33.50%) presented with anxiety status and 81(41.12%) with depression status.Comorbidity [OR=2.25,95%CI:(1.20,4.25)] and the number of perianal surgeries ≥2 times [OR=2.15,95%CI:(1.17,3.96)] were risk factors for depressive state in PFCD patients;comorbidity [OR=2.27,95%CI:(1.19,4.34)] and disease activity [OR=2.58,95%CI:(1.04,6.42)] were risk factors for the development of anxiety in PFCD patients.Conclusions Patients with CD combined with perianal fistula have a high incidence,long duration and difficult treatment.Patients often have emotional stress due to systemic conditions and perianal fistula,and attention should be given to patients’ mental health while treating the disease clinically.
作者
赵访访
陈玉根
冯泽宇
周巧
ZHAO Fangfang;CHEN Yugen;FENG Zeyu;ZHOU Qiao(Department of Anorectal Surgery,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing,Jiangsu 210000,China;Department of Anorectal Surgery,Wuxi Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Wuxi,Jiangsu 214000,China)
出处
《安徽医药》
CAS
2022年第12期2429-2433,共5页
Anhui Medical and Pharmaceutical Journal
关键词
CROHN病
直肠瘘
焦虑
抑郁
影响因素
Crohn’s disease
Rectal fistula
Anxiety
Depression
Influencing factor
