摘要
5-氨基水杨酸(5-ASA)是临床应用最早、不良反应最少、使用最多的治疗炎症性肠病(IBD)的药物,但实际应用中仍存在诸多不规范的情况。本文从5-ASA用于IBD治疗的发展史和治疗机制、5-ASA在IBD中的合理应用、5-ASA对IBD相关结直肠癌的预防作用以及5-ASA的不良反应4个方面介绍其在IBD中的应用,旨在全面了解5-ASA在IBD治疗中的作用,使其更合理、规范地应用于临床。
5 aminosalicylic acid （5-ASA） is the earliest medication widely used for inflammatory bowel disease （IBD） treatment with little side effect. However, improper use of drugs often appear in clinic. The present article mainly introduced the development history, therapeutic mechanism,reasonable application and side effect of 5-ASA in IBD treatment as well as its chemopreventive effect on IBD-associated colonic cancer with the purpose of 5 ASA beneficial use.
出处
《临床荟萃》
CAS
2016年第8期820-823,共4页
Clinical Focus
关键词
炎性肠疾病
结直肠肿瘤
5-氨基水杨酸
治疗
inflammatory bowel disease
colorectal neoplasms
5-aminosalicylic acid
treatment
