摘要
目的探讨妥布霉素地塞米松滴眼液治疗睑缘炎的临床疗效。方法将2012年10月至2014年12月于某院治疗的100例睑缘炎患者利用随机数字表分为观察组和对照组各50例,对照组采用红霉素眼膏而观察组采用妥布霉素地塞米松滴眼液治疗,比较两组之间的疗效、泪膜情况评分、睑板腺分泌物评分、泪膜破裂时间以及不良反应情况。结果观察组治疗后的总有效率为82.00%,显著高于对照组的60.00%,差异有统计学意义(P<0.05)。观察组治疗后的泪膜情况评分、睑板腺分泌物评分、泪膜破裂时间以及泪液分泌量均优于对照组,差异有统计学意义(P<0.05)。两组患者的不良反应发生率差异无统计学意义(P>0.05)。结论妥布霉素地塞米松滴眼液治疗睑缘炎可显著改善患者的临床症状,提高治愈率,且不良反应少,安全性高。
Objective To investigate the effect of tobramycin and dexamethasone eye drop on blepharitis.Methods In accordance with random number table,100 patients with blepharitis in a hospital from Oct 2012 to Dec 2014 were divided into two groups,with 50 patients treated with erythromycin eye ointment as the control group and 50 patients treated with tobramycin and dexamethasone ophthalmic ointment as the observation group.The effect,tear-film scores,meibomian gland secretion scores,breakup time of tear film and adverse reactions were compared between the two groups.Results The total effective rate in the observation group was 82.00%,significant higher than that of the control group 60.00%and the difference was statistically significant(P<0.05).The tear film score,meibomian gland secretion score,tear film break-up time and tear secretion of the observation group after treatment were better than those of the control group and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Tobramycin and dexamethasone eye drop was an effective drug in treatment of blepharitis,significantly improving clinical symptoms and rate.Tobramycin and dexamethasone eye drop had fewer adverse reactions and was safe.
出处
《中国疗养医学》
2018年第4期424-426,共3页
Chinese Journal of Convalescent Medicine
