摘要
背景:目前对于腰椎退变性疾病及下腰痛患者中Modic改变的研究较多,但有关颈肩痛患者颈椎Modic改变的研究少见,有关其流行病学分布特点及相关影响因素尚存在争议。目的:分析颈肩痛患者中Modic改变的发生率、分布特点及其与性别、年龄、与颈椎退变的相关性。方法:回顾性分析2014年12月至2016年12月因颈肩痛就诊于内蒙古医科大学第二附属医院并行颈椎MRI及CT检查的患者430例,其中男197例,女233例;年龄19-78岁,平均50.3岁。分析Modic改变发生率、节段分布特点及其与年龄、性别、颈椎间盘退变和小关节退变的相关性。结果与结论:(1)430例2 150个椎间盘中共有67例(15.6%)348个(16.2%)椎间盘节段发生Modic改变:Ⅰ型73个(3.4%),Ⅱ型243个(11.3%),Ⅲ型32个(1.5%);(2)应用多组频数分布的卡方检验,Modic改变最常见于C_(5/6)节段;好发于40岁以上人群、Pfirrmann间盘退变Ⅲ期及以上节段;与性别及小关节退变无相关性。
BACKGROUND:There are many studies on Modic changes in patients with lumbar degenerative disease and low back pain.However,few studies facus on epidemiological distribution and related factors of Modic changes in cervical spine,and its epidemiology and influencing factors remain unclear.OBJECTIVE:To study the morbidity and distribution of Modic changes in patients with cervical and shoulder pain and its correlation with gender,age and cervical degeneration.METHODS:Totally 430 patients admitted in the Second Affiliated Hospital of Inner Mongolia Medical University and undergoing cervical MRI and CT examination due to neck and shoulder pain between December 2014 and December 2016 were retrospectively analyzed,involving 197 males and 233 females,aged 19-78 years(mean age:50.3 years).The morbidity and segmental distribution of Modic changes and its correlation with age,sex,cervical intervertebral disc degeneration and facet joint degeneration were analyzed.RESULTS AND CONCLUSION:(1)Among 2 150 disc segments of 430 patients,348 segments(16.2%)of 67 patients(15.6%)appeared with Modic changes:73(3.4%)segments were type I,243(11.3%)were type II,and 32(1.5%)were type III.(2)By application of chi-square test,Modic changes were most common at the C5/6 segment;older than 40 years and Pfirrmann disc degeneration grade III were relevant factors,while gender and facet joint degeneration were not.
作者
李文选
于宝龙
张沛
李瑞峰
贾岩波
Li Wen-xuan;Yu Bao-long;Zhang Pei;Li Rui-feng;Jia Yan-bo(Department of Cervical Spine Surgery,the Second Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010030,Inner Mongolia Autonomous Region,China;Department of Orthopedics,the Second Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010030,Inner Mongolia Autonomous Region,China)
出处
《中国组织工程研究》
CAS
北大核心
2018年第3期432-437,共6页
Chinese Journal of Tissue Engineering Research
基金
内蒙古自治区自然科学基金(2015MS0895),课题名称:维生素E对激素性股骨头坏死氧化应激途径相关基因表达的影响研究
关键词
颈椎
颈痛
肩痛
椎间盘
组织工程
Cervical Spine
Modic Change
Incidence
Degeneration
