摘要
目的研究口服轮状病毒疫苗预防小儿腹泻的效果。方法 120例接受保健治疗的儿童,随机分为对照组与观察组,各60例。对照组儿童未服用轮状病毒疫苗,观察组儿童口服轮状病毒疫苗,比较两组随访1年的腹泻发生率、腹泻发病严重程度等。结果随访1年,观察组儿童腹泻发生率为13.33%,低于对照组的31.67%,差异有统计学意义(P<0.05);观察组患儿腹泻程度轻于对照组,差异有统计学意义(P<0.05);观察组腹泻患儿1年内的发病次数为(1.76±0.33)次,少于对照组的(3.10±0.46)次,差异有统计学意义(P<0.05)。结论预防性口服轮状病毒疫苗有助于预防小儿腹泻的发生,有助于降低发病患儿病情的严重程度,促进患儿的早日康复,值得在儿童预防保健工作中推广应用。
Objective To study the effect of oral rotavirus vaccine in prevention and treatment of infantile diarrhea.Methods A total of120children receiving hearth care were randomly divided into control group and observation group,with60cases in each group.The control group received no rotavirus vaccine,and the observation group received oral rotavirus vaccine.Comparison were made on incidence of diarrhea and severity of diarrhea in two groups during1year of follow-up.Results During1year of follow-up,the observation group had lower incidence of diarrhea as13.33%than31.67%in the control group,and the difference had statistical significance(P<0.05).The observation group had lighter severity of diarrhea than the control group,and the difference had statistical significance(P<0.05).The observation group had less frequency of diarrhea as(1.76±0.33)times than(3.10±0.46)times in the control group in1year,and the difference had statistical significance(P<0.05).Conclusion Preventive oral rotavirus vaccine can help prevent the occurrence of diarrhea in children,reduce the severity of the disease and promote the early rehabilitation of children.So it is worthy of popularization and application of preventive health care in children.
作者
邹国涛
罗敏珊
吴源渊
ZOU Guo-tao;LUO Min-shan;WU Yuan-yuan(Shenzhen Baoan District Fuyong People’s Hospital Peace Community Health Service Center, Shenzhen 518103, China)
出处
《中国现代药物应用》
2017年第17期101-103,共3页
Chinese Journal of Modern Drug Application
关键词
轮状病毒疫苗
小儿腹泻
预防保健
发病次数
Rotavirus vaccine
Infantile diarrhea
Preventive health care
Frequency
