摘要
目的探讨实时三维超声心动图(Real Time Three Dimensional Echocardiography,RT-3DE)对系统性红斑狼疮(Systemic Lupus Erythematosus,SLE)合并肺动脉高压(Pulmonary Arterial Hypertension,PAH)患者右心功能评价效果。方法选取2015年3月~2016年2月间于我院治疗的SLE合并PAH患者共54例(观察组),另选同期于我院体检的健康志愿者54例(对照组)。将观察组患者以PAH程度分为轻度组(肺动脉收缩压在35~50 mm Hg之间,30例)及中重度组(肺动脉收缩压>50 mm Hg,24例)。对比观察各组患者右心室收缩末期容积(Right Ventricular EndSystolic Volume,RVESV)、舒张末期容积(Right Ventricular End-Diastolic Volume,RVEDV)、每搏量(Stroke Volume,SV)、射血分数(Right Ventricular Ejection Fraction,RVEF)、舒张末期面积(Right Ventricular End-Diastolic Area,RVEDA)、收缩末期面积(Right Ventricular End-Systolic Area,RVESA)、收缩末期面积(Systolic Stage Area,RAA)、面积变化率(the Rate of Area Change,FAC)、舒张末期右心室与左心室内径之比(Right Ventricular And Left Ventricular,RV/LV)、三尖瓣口血流速度(E、A)、瓣环运动速速[二尖瓣环舒张期运动速度E峰(e’)、A峰(a’)、二尖瓣环收缩期运动速度(s’)]、右心做功指数(Myocardial Performance Index,MPI)、肺动脉收缩压等情况。结果轻度组和中重度组患者右心室RVEDV、RVEF及RVESV值均显著高于正常对照组,差异有统计学意义(t=7.896;8.039;9.031,P<0.05),而SV差异无统计学意义(P>0.05);中重度组患者右心室RVEDV、RVEF及RVESV值均显著高于轻度组,差异有统计学意义(t=8.534;8.127;9.542,P<0.05),而SV差异无统计学意义(P>0.05);对轻度组及中重度组与对照组间的年龄(t=-1.237;0.145)、收缩压(t=1.543;0.761)、舒张压(t=2.013;0.308)及体质量指数(t=-1.779;1.381)两两比较,差异均不具有统计学意义(P>0.05);中重度组心率与其他各组相比差异均有统计学意义(t=7.893;1.608,P<0.05);与对照组对比,轻度组及中重度�
Objective To evaluate right ventricular functional assessment of the effectiveness of application of Real Time Three-Dimensional Echocardiography (RT-3DE) in diagnosis of patients sufered Pulmonary Hypertension (PAH) along with Systemic Lupus Erythematosus (SLE). Methods A total of 54 patients with PAH and SLE were treated in the hospital between March 2015 to February 2016 (Observation Group), 54 healthy volunteers in the hospital were selected as the study group during the same period. According to the degree of PAH, the Observation Group were divided into mild group (pulmonary artery systolic pressure between 35～50 mmHg, 30 cases) and severe group (systolic pulmonary artery pressure>50 mmHg, 24 cases). Comparative analysis of Right Ventricular End-Systolic Volume (RVESV), End-Diastolic Volume (RVEDV), Stroke Volume (SV), Ejection Fraction (RVEF), End-Diastolic Area (RVEDA), End-Systolic Area (RVESA), Systolic Stage Area (RAA), the rate of area change (FAC), Right Ventricular and Left Ventricular enddiastolic inner diameter ratio (RV/LV), tricuspid inflow velocities (E, A), annulus motion haste (s', e', a'), right ventricular myocardial performance index (MPI) and systolic pulmonary artery pressure among groups. Results Compared with Control Group, mild group and severe group showed obviously increasing right ventricle RVEDV, RVEF and RVESV values with significant differences (t=7.896; 8.039; 9.031, P<0.05), no statistically significant differences in SV (P>0.05); compared with mild group, severe group showed obviously increasing right ventricle RVEDV, RVEF and RVESV values with significant differences (t=8.534; 8.127; 9.542, P<0.05), there is no statistically significant differences in SV (P>0.05); compared with each groups, age (t=-1.237; 0.145), systolic blood pressure (t=1.543; 0.761), diastolic blood pressure (t= 2.013; 0.308 ) and body mass index (t=-1.779; 1.381) without statistically significant differences (P>0.05); the heart rate between severe group and other groups with statistically significant d
作者
曹白羽
CAO Bai-yu(Department of Diagnosed Electrical,Siping First People’s Hospital, Siping Jilin 136001, China)
出处
《中国医疗设备》
2017年第4期74-78,共5页
China Medical Devices
关键词
实时三维超声心动图
右心功能
系统性红斑狼疮
肺动脉高压
彩色多普勒超声
real time three-dimensional echocardiography
right ventricular function
systemic lupus erythematosus
pulmonary hypertension
color Doppler ultrasound
