摘要
背景:急性排斥反应是关系到心脏移植后能否长期存活的关键因素之一,因此及时发现并控制急性排斥反应在临床实践中尤为重要。目的:探讨心脏移植后超声心动图检测的临床意义。方法:通过检索近年来关于超声心动图对移植心脏进行检查的临床研究及动物实验相关文献,分析移植心脏心动图特点,供者心脏在受者体内发生的结构和功能的变化,测量并比较相关指标,以评价超声心动图在心脏移植急性排斥反应中的价值。结果与结论:超声心动图检查可及时无创的监测心脏移植后排斥反应,在移植前受体评价、移植中监测及移植后随访中都为临床诊治提供重要的参考依据,但由于病例数较少,且由于心脏移植患者在移植后的不同时间段进行检测,可能对研究的结果造成影响,有待于今后对心脏移植患者在移植后的相同时间段进行评价,使研究结果更具有可比性及准确性。
BACKGROUND： Acute rejection is a key factor for long survival of transplanted heart. Therefore, discovering and controlling acute rejections in time is very important in clinical practice.OBJECTIVE： To investigate the clinical significance of ultrasoundcardiogram after heart transplantation.METHODS： Recently published articles concerning clinical and animal research on ultrasoundcardiogram following heart transplantation were searched. Then, we analyzed the features of ultrasoundcardiogram of transplanted heart, structural and functional changes of donor hearts in the recipients. Relevant markers were measured and compared to evaluate the effect of ultrasoundcardiogram against acute rejections after heart transplantation.RESULTS AND CONCLUSION： Ultrasoundcardiogram can invasively monitor acute rejections after heart transplantation in time, and also can provide important references for pre-transplantation recipient evaluation, intra-transplantation monitoring, and post-transplantation follow-up. However, lack of cases and post-transplantation monitoring in different periods may impact our findings. Post-transplantation monitoring in the same period can improve the comparativeness and accuracy of the study.
出处
《中国组织工程研究》
CAS
CSCD
2013年第53期9221-9226,共6页
Chinese Journal of Tissue Engineering Research
