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药物涂层球囊血管成形术治疗股腘动脉支架内再狭窄的效果 被引量:3

Efficacy of drug-coated balloon angioplasty on in-stent restenosis of femoral-popliteal artery
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摘要 目的探讨股腘动脉支架内再狭窄采用药物涂层球囊血管成形术治疗的效果。方法回顾性分析2015年2月至2018年1月94例股腘动脉支架内再狭窄患者的临床资料,依据治疗方式不同分为两组。试验组44例采用药物涂层球囊血管成形术治疗,对照组50例采用普通球囊血管成形术治疗。术后随访6个月,比较两组Rutherford分级、靶病变血运重建(TLR)发生率、一期通畅率、再狭窄率、靶血管最小管腔直径(MLD)、踝肱指数(ABI)、并发症。结果试验组Rutherford分级优于对照组,TLR发生率、再狭窄率低于对照组,一期通畅率高于对照组,差异有统计学意义(P<0.05)。术后6个月,试验组ABI、MLD高于对照组,差异有统计学意义(P<0.05)。两组并发症发生率比较,差异未见统计学意义(P>0.05)。结论股腘动脉支架内再狭窄采用药物涂层球囊血管成形术治疗可提升一期通畅率,改善ABI、MLD水平,降低再狭窄率,利于患者预后。 Objective To investigate the efficacy of drug-coated balloon angioplasty on in-stent restenosis(ISR)of femoral-popliteal artery.Methods The clinical data of 94 patients with ISR of femoral-popliteal artery from February 2015 to January 2018 were retrospectively analyzed.All patients were divided into two groups by treatment methods.Experimental group(44 cases)took drug-coated balloon angioplasty,while control group(50 cases)was treated with plain old balloon angioplasty.During postoperative 6 months of follow-up,the Rutherford grading,incidence of target lesion reconstruction(TLR),one-stage patency rate,restenosis rate,target vessel minimal lumen diameter(MLD),ankle-brachial index(ABI),complications were compared between the two groups.Results The Rutherford grading of experimental group was better than that of control group,the incidence of TLR and restenosis rate in experimental group were lower than those in control group,the one-stage patency rate of experimental group was higher than that of control group(P<0.05).After surgery for 6 months,the ABI and MLD in experimental group were higher than those in control group(P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusions Drug-coated balloon angioplasty in treatment of ISR of femoral-popliteal artery can increase the one-stage patency rate,improve the levels of ABI and MLD,decrease the restenosis rate,and promote the prognosis of patients.
作者 吴延庆 Wu Yanqing(Department of Vascular Surgery,the First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,China)
出处 《临床医学》 CAS 2019年第8期18-20,共3页 Clinical Medicine
关键词 股腘动脉支架内再狭窄 药物涂层球囊血管成形术 普通球囊血管成形术 In-stent restenosis of femoral-popliteal artery Drug-coated balloon angioplasty Plain old balloon angioplasty
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