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定量超声测量甲亢患者骨质变化的临床价值

Clinical value of bone quality changes in hyperthyroid patients with quantitative ultrasound
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摘要 目的研究定量超声法测量甲亢患者骨质变化的临床价值。方法用定量超声法测量了347例存在高T3和T4的甲亢患者及性别和年龄相匹配的健康对照组的右跟骨超声参数:超声振幅衰减(BUA)和超声传导速度(SOS)。结果甲亢患者的BUA值明显低于正常对照组(P< 0.01),骨质量丢失发生率明显高于正常对照组。BUA、SOS与T3、T4、促甲状腺激素(TSH)之间均无明显相关关系(|r|< 0.15,p >0.05)。结论定量超声参数可以敏感地检测甲亢对骨质量的影响。 Objective To evaluate bone quality changes in hyperthyroid patients with quantitative ultrasound (QUS).Methods The QUS parameters of BUA and SOS at the right calcanens were measured in 347 hyperthyroid patients with raised serum triiodothvronine (T3)and thyroxine(T4),and compared with an age and sex-matched control groups .Results BUA was significantly lower in hyperthyroid patients than that in controls(P&lt; 0.01).Incidences of bone quality loss was higher in hyperthyroid patients than that in controls .No significant correlation were found bettween ultrasound variabes and T3、T4 、TSH(|r|&lt; 0.15,P &gt;0.05).Conclusion QUS parameters permit acsessment of the effect of byperehyroidisim on bone density.
出处 《中国组织工程研究》 CAS CSCD 2001年第7期92-93,共2页 Chinese Journal of Tissue Engineering Research
关键词 甲亢 骨密度 骨质疏松症 跟骨-超声学 hyperthyroidism bone density osteoporosis calcaneus ultra sonometry
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