摘要
目的深入研究在临床治疗良性甲状腺结节中应用小剂量左甲状腺素的临床应用成效。方法随机筛选于2013年1月至2018年1月入院接受诊治的100例良性甲状腺结节患者,平均分配为治疗组与对照组,各为50例。对照组(n=50)应用安慰剂进行治疗,治疗组(n=50)应用小剂量左甲状腺素。将两组的TSH、FT4、FT3等生化指标、甲状腺体积、不良反应情况进行分析与比较。结果两组的FT3比较差异不存在统计学意义(P>0.05);治疗组的TSH、甲状腺体积均低于对照组(P<0.05);经治疗后的TSH、甲状腺体积均低于治疗前(P<0.05);治疗组的FT4高于对照组(P<0.05);相比于对照组,治疗组的不良反应较少(P<0.05)。结论在临床治疗良性甲状腺结节中应用小剂量左甲状腺素,治疗成效可观,能够降低血脂,有利于改善预后,医疗价值高。
0bjective To study the clinical application of low-dose levothyroxine in clinical treatment of benign thyroid nodules. Methods Randomly selected 100 patients with benign thyroid nodules admitted to hospital from January 2013 to January 2018. The average allocation was in the treatment group and the control group, 50 eases in each group. The control group （n=50） was treated with placebo, while the treatment group （n=50） was treated with low dose of levothyroxine. Two groups of TSH, FT4, FT3 and other biochemical indicators, thyroid volume, adverse reactions were analyzed and compared. Results The difference of FT3 between the two groups was not statistically significant （P〉0.05）; the TSH and thyroid volume of the treatment group were lower than those of the control group （P〈0.05）. The volume of TSH and thyroid after treatment was lower than that before treatment （P〈0.05）, and the FT4 in the treatment group was higher than that of the control group （P〈0.05）, and the adverse reaction of the treatment group was less than that of the control group （P〈0.05）. Conclusion The application of low dose levothyroxine in the clinical treatment of benign thyroid nodules is significant, can reduce blood lipid, improve the prognosis, and have high medical value.
作者
陈可峰
CHEN Ke-feng(Jimo District People＇s Hospital,Qingdao,Shandong,26620)
出处
《智慧健康》
2018年第11期110-111,共2页
Smart Healthcare
