摘要
目的结肠癌主要由遗传及不良饮食习惯等因素引起,是常见的消化系统恶性肿瘤,腹腔镜结肠癌根治术以其微创性被广泛应用于临床。本研究对比分析腹腔镜结肠癌根治术与开传统腹手术治疗结肠癌近远期疗效。方法回顾性分析2012-03-01-2013-02-28郑州市第六人民医院收治的252例结肠癌患者的临床资料,根据手术方式不同分为腹腔镜组和开腹组,每组126例。腹腔镜组给予腹腔镜结肠癌根治术,开腹组采用传统开腹手术治疗,比较两组近期疗效和远期疗效。结果腹腔镜组手术时间为(199.37±14.29)min,低于开腹组的(173.76±15.29)min,t=13.736,P=0.034;腹腔镜组术中出血量为(93.28±11.35)mL,低于开腹组的(204.75±18.94)mL,t=56.668,P=0.017;腹腔镜组术后排气时间为(2.15±0.36)d,短于开腹组的(3.37±0.98)d,t=13.117,P=0.036;腹腔镜组下床活动时间为(80.37±8.45)h,短于开腹组的(107.62±11.38)h,t=21.580,P=0.024;腹腔镜组住院时间(8.62±1.34)d,短于开腹组的(11.78±2.56)d,t=12.276,P=0.038。腹腔镜组和开腹组术后并发症发生率为3.17%和4.76%,差异无统计学意义,χ2=0.417,P=0.519;腹腔镜组和开腹组局部复发率为1.59%和2.38%,差异无统计学意义,χ2=0.204,P=0.651;腹腔镜组和开腹组远处转移率为5.56%和4.76%,差异无统计学意义,χ2=0.081,P=0.776;腹腔镜组和开腹组转移复发率为7.94%和8.73,差异无统计学意义,χ2=0.052,P=0.820;腹腔镜组和开腹组3年生存率为42.63%和43.65%,差异无统计学意义,χ2=0.065,P=0.799;腹腔镜组和开腹组5年生存率为14.29%和15.08%,差异无统计学意义,χ2=0.032,P=0.859。结论腹腔镜结肠癌根治术可达到与开腹手术相当的近远期疗效,且具有创伤小、恢复快等优势。
OBJECTIVE Colon cancer is mainly caused by heredity and unhealthy eating habits.It is a common malignant tumor of digestive system.Laparoscopic radical resection of colon cancer is widely used in clinic with minimal invasion.This study compared the short-term and long-term outcomes of laparoscopic radical resection and conventional abdominal surgery for colon cancer.METHODS A retrospective analysis was performed of 252 cases with colon cancer treated in Sixth People＇s Hospital of Zhengzhou from March 1,2012 to February 28,2013.The cases were divided into laparoscopy group and laparotomy group according to different surgical methods,with 126 cases in each group.The laparoscopic group was given laparoscopic radical resection of colon cancer,and the open group was treated by traditional laparotomy.The short-term and long-term effects of the two groups were compared.RESULTS The operative time of laparoscopic group was（199.37±14.29）min,obviously lower than that of laparotomy group（173.76±15.29）min,t=13.736,P〈0.01;The bleeding volume in the laparoscopic group was（93.28±11.35）mL,lower than that in the laparotomy group（204.75±18.94）mL,t=56.668,P〈0.01;The postoperative exhaust time of the laparoscopic group was（2.15±0.36）d,shorter than that of the laparotomy group（3.37±0.98）d,t=13.117,P〈0.01;Postoperative activity time in laparoscopic group was（80.37±8.45）h,shorter than that in laparotomy group（107.62±11.38）h,t=21.580,P〈0.01;Hospital stay in the laparoscopic group was（8.62±1.34）d,shorter than that in the laparotomy group（11.78±2.56）d,t=12.276,P〈0.01.There were no statistic differences between laparoscopic group and laparotomy group in incidence of postoperative complications（3.17% vs 4.76%）,local recurrence rate（1.59% vs 2.38%）,distant metastasis rate（5.56% vs 4.76%）and recurrence rate（7.94% vs 8.73%）.The 3-year and 5-year survival rates of the laparoscopic group（42.63% vs 14.29%）had no significant difference compared with those of the lapar
作者
林庆刚
LIN Qing-gang(Sixth People＇s Hospital of Zhengzhou,Zhengzhou 450000 ,P. R. China)
出处
《社区医学杂志》
2018年第13期1097-1100,共4页
Journal Of Community Medicine
关键词
结肠癌
腹腔镜手术
开腹手术
近期疗效
远期疗效
colon cancer
laparoscopic surgery
laparotomy
short term efficacy
long-term efficacy
