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肾脏裂伤:人的羊膜包肾的动物定验 被引量:1

An Experimental Study on Human Amnion as Biological Dressing for Renal Lacerations in Dogs
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摘要 杂交犬11只,一侧肾脏以持骨钳夹成多处深层裂伤,5只犬用新鲜羊膜包裹,用甘油或戊二醛处理过的羊膜包裹者各3只。术后,5只动物分别在不同时间出现不良反应,其中3例死亡。其余8只犬经6个月的观察,B型超声仪检查伤肾未见异常,切除肾脏,与周围仅轻微粘连,外观可见愈合良好之瘢痕。羊膜、腹腔棉拭子培养无细菌生长。通过实验我们认为:人的羊膜可作为一种修复肾脏裂伤的有效材料,尤其甘油处理的羊膜,不仅韧性好,而且便于保存。 The purpose of this study is to look for an ideal and easily obtainable and preservable material for repair of the renal laceration wounds. 11 mongrel dogs were employed and their kidneys were pinched to result in multiple deep lacerations. Fresh human amnion was used to dress the renal wounds in 5 dogs, glycerinized amnion in 3 dogs and glutaraldyhydized amnion in the remainders.Postoperative adverse reactions were observed in 5 dogs, of them 3 eventually died. The kidneys of the 8 surviving dogs showed no abnormal alteration under ultrasonography during 6 monthes follow up observation. On the naked eye examination in nephrectomy found, there was only a little adhesion around the sites of original lacerations. Bacterial culture in the place was negative. It is concluded that human amnion is a good biological dressing for repair of renal lacerations and the glycerinized amnion is easy to obtain and to be preserved.
出处 《中华创伤杂志》 CAS CSCD 北大核心 1991年第3期145-146,共2页 Chinese Journal of Trauma
关键词 羊膜 肾裂伤 Amnion Renal laceration
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