摘要
本研究主要是探讨非酒精性脂肪肝(non-alcoholic fatty liver disease,NAFLD)超声诊断与血糖血脂、体质量指数(body mass index,BMI)的关系。分析2017年10月16日至2018年1月12日期间654例某大学在职与退休教职工为期两个多月的职工体检资料,分析NAFLD超声诊断与空腹血糖(fasting blood-glucose,FPG)、总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、BMI及乙肝病毒(HBV-DNA)载量的关系。超声诊断NAFLD 222例,占33. 94%,其中轻度占50. 90%(113/222),中度占37. 84%(84/222),重度占11. 26%(25/222)。男性组NAFLD发生率明显高于女性组,P <0. 05。男性组(NAFLD组)高血糖、TG阳性与肥胖症所占比例均明显高于女性组(非NAFLD组),身高、体质量、BMI与FBG均高于女性组(非NAFLD组),P <0. 05。男性组(NAFLD组)乙肝病毒(HBV-DNA)载量高于女性组(非NAFLD组),但比较差异无统计学意义(P> 0. 05)。结果表明,NAFLD常见于男性群体,并以血糖血脂异常与肥胖为主要特征,控制TC、TG、BMI与FBG水平对NAFLD的防治具有重要的意义,而持续监测HBVDNA载量对于指导抗病毒治疗也意义重大。
The objective of this study is determine the relationship between non-alcoholic fatty liver disease（NAFLD）in ultrasonic diagnosis and blood lipid,body mass index（BMI）. The physical examination data of 654 worker cases of serving and retired staff in a university during a period of two months from October 16 th 2017 to January 12 th 2018 were prospectively analyzed,the relationship between NAFLD ultrasonic diagnosis and fasting blood-glucose（FPG）,total cholesterol（TC）,triglyceride（TG）,body mass index. Ultrasonic diagnosed NAFLD 222 cases,accounted for 33. 94%,which mild accounted for 50. 90%（113/222）,moderate accounted for 37. 84%（84/222）,severe accounted for 11.26%（25/222）. The incidences rates of NAFLD in male group were significantly higher than those in female group. The incidences rates of hyperglycemia,TG positive and obesity height,body mass,BMI and FBG in male（NAFLD） groups were significantly higher than those in female（non-NAFLD） groups,P 0. 05. HBV-DNA load in male（NAFLD） groups were higher than female（non-NAFLD） groups,whereas the comparison had no significant differences,P〈 0. 05. It is found that NAFLD is commonly occurred in male,and the pathoglycemia,dyslipidemia and obesity are as its main characteristics,it plays vital significance in controlling the levels of TC,TG,BMI and FBG for the prevention and treatment of NAFLD. However continuously monitoring HBVDNA loads is of great importance in directing antiviral treatment.
作者
王玮
WANG Wei(Color Ultrasonic Room of Yanshan University Hospital,Qinhuangdao 066004,Hebei,China)
出处
《激光生物学报》
CAS
2018年第4期349-353,366,共6页
Acta Laser Biology Sinica
关键词
非酒精性脂肪肝
超声
血脂
体质量指数
non-alcoholic fatty liver disease
ultrasound
blood lipid
body mass index
