摘要
目的:观察健脾消胀丸治疗脾虚气滞型功能性消化不良的临床疗效。方法:选取92例脾虚气滞型功能性消化不良患者,并按入院先后顺序分为治疗组(n=47)与对照组(n=45)。2组均给予饮食控制,其中对照组给予西药盐酸依托必利颗粒+雷贝拉唑肠溶片治疗,治疗组给予自制健脾消胀丸治疗。观察评估2组中医症候积分、临床疗效及不良反应。结果:治疗组总有效率为89.36%,对照组总有效率为71.11%,2组比较,差异有统计学意义(P <0.05)。治疗前,2组中医症候积分比较,差异无统计学意义(P> 0.05)。治疗后,2组中医症候积分较治疗前均显著降低(P <0.05),治疗组中医症候积分显著低于对照组(P <0.05)。治疗组不良反应发生率为4.26%,对照组不良反应发生率为20.00%,2组比较,差异有统计学意义(P <0.05)。结论:针对脾虚气滞型功能性消化不良患者,给予健脾消胀丸治疗可有效改善患者临床症状,提高临床治疗效果,且治疗后不良反应发生率低,值得临床推广应用。
Objective： To observe the clinical effect of Jianpi Xiaozhang pills for functional dyspepsia of spleen-deficiency and qi-stagnation type. Methods： Selected 92 cases of patients of with functional dyspepsia of spleen-deficiency and qi-stagnation type and divided them into the treatment group（n=47） and the control group（n=45） according to the order of admission. The two groups were both given diet control. The control group was treated with western medicine itopride hydrochloride granules combined with rabeprazole enteric-coated tablets, while the treatment group was given self-made Jianpi Xiaozhang pills. Observed and evaluated the Chinese medicine syndrome scores,clinical effect and adverse reactions in the two groups. Results：The total effective rate was 89.36% in the treatment group and 71.11% in the control group, difference being significant（P〈0.05）. Before treatment, there was no significant difference being found in the comparison of Chinese medicine syndrome scores between the two groups（P〉0.05）. After treatment,the Chinese medicine syndrome scores in the two groups were significantly decreased when compared with those before treatment（P〈0.05）,and the Chinese medicine syndrome scores in the treatment group were evidently lower than in the control group（P〈0.05）. The incidence of adverse reactions was 4.26% in the treatment group and 20.00% in the control group,difference being significant（P〈0.05）.Conclusion：The application of Jianpi Xiaozhang pills for patients with functional dyspepsia of spleen-deficiency and qi-stagnation type can effectively improve the clinical symptoms and promote the clinical effect with low incidence of adverse reactions after treatment. It is worthy of clinical promotion and application.
出处
《新中医》
CAS
2018年第10期73-76,共4页
New Chinese Medicine
基金
山东省中医药科技发展计划项目(2017-308)
关键词
功能性消化不良
脾虚气滞型
健脾消胀丸
中医症候评分
临床疗效
Functional dyspepsia
Spleen-deficiency and qi-stagnation type
Jianpi Xiaozhang pills
Chinese medicinesyndrome scores
Clinical effect
