摘要
目的:探讨2008～2013年河南省林州市食管癌发病的变化规律,为制定防治策略提供数据支持。方法:提取2008～2013年河南省林州市肿瘤登记处的食管癌发病数据,分性别、年龄别计算发病率和标准化人口年龄结构调整的发病率。采用Joinpoint软件分析近几年食管癌发病率的变化趋势,采用对数线性回归计算年平均变化百分比。结果:2008～2013年河南省林州市食管癌共新发病例5 460例,粗发病率为85. 98/10万;中国人口标准化发病率(中标率)为71. 60/10万,世界人口标准化发病率(世标率)为72. 46/10万。2008～2013年,该地区食管癌发病率平均每年降低1. 98%[年平均变化率(AAPC)为-1. 98%,95%CI为-3. 43%～-0. 51%],其中女性较男性下降明显。调整人口结构后,食管癌中标率平均每年以5. 21%的幅度下降(AAPC为-5. 21%,95%CI为-7. 76%～-2. 60%),世标率平均每年以5. 23%的幅度下降(AAPC为-5. 23%,95%CI为-8. 12%～-2. 25%)。结论:食管癌是河南省林州市最常见的恶性肿瘤,是肿瘤防治工作的重点,通过长期危险因素的预防控制及筛查技术的普遍开展,该地区食管癌的发病率呈现逐年下降趋势。
Objective： To investigate changes in the incidence of esophageal cancer in Linzhou, Henan, from 2008 to 2013, so as to provide evidence for the formulation of the prevention and control strategies for esophageal cancer. Methods： Data on esophageal cancer from 2008 to 2013 were obtained from Central Cancer Registry in Linzhou, Henan. Incidenee of esophageal cancer, and age-standardized incidence rates were calculated by sex and age. The incidence trend of esophageal cancer was analysed by Joinpoint, the annual average percentage change （AAPC） was calculated by log line- ar regression. Results： The new cases of esophageal cancer were 5460 from 2008 to 2013 in Linzhou. The incidence rate was 85.98/105, the age-standardized incidence rate by Chinese standard population and that by world population were 71.60/105 and 72.46/105 respectively. There was a downward trend in the incidence rate of esophageal cancer from 2008 to 2013 with an AAPC of -1.98% （95CI： -3.43% - -0.51% ）. After age standardization, the age-standardized inci- dence rate by Chinese standard population and that by world population significantly decreased, with an AAPC of - 5.21% （95%CI： -7.76% - -2.60% ） and of -5.23% （95%CI： -8.12% to -2.25% ） respectively. Conclusion： Esoph- ageal cancer is the most common cancer in Linzhou, Henan, and is a priority in the cancer prevention and treatment. After long-term prevention and control of risk factors and the prevalence of screening techniques, incidence of esophageal cancer has a downward trend.
作者
冯爽
于晓东
李变云
邵毅
魏文强
郭秀花
刘芬
Feng Shuang;Yu Xiaodong;Li Bianyun;Shao Yi;Wei Wenqiang;Guo Xiuhua;Liu Fen(Department of Epidemiology and Medical Statistics,School of Public Health,Capital Medical University,Key Laboratory of Clinical Epidemiology in Beijing,Beijing 100069,China;Linzhou Cancer Hospital,Linzhou 456550,Henan,China;National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences,Beijing Union Medical College of Epidemiology,Beijing 100021,China;Preventive Health Branch of Beijing Haidian Maternal and Child Health Hospital,Belting 10080,China)
出处
《肿瘤预防与治疗》
2018年第5期347-351,共5页
Journal of Cancer Control And Treatment
基金
国家自然科学基金资助项目(编号:81473056、81573224)
北京市自然科学基金资助项目(编号:7172025)
北京市教委科研计划一般项目(编号:KM201710025006)
国家“十三五”科技支撑计划项目课题(编号:2016YFC1302804)
关键词
食管癌
发病率
发病趋势
Esophageal cancer
Incidence
Trend
