摘要
目的分析冷沉淀在消化道急性大出血中的应用效果。方法选择2015年1月—2017年12月在我院接受输血治疗的消化道急性大出血患者244例,随机分成对照组及观察组,每组各122例,对照组输注新鲜冰冻血浆,观察组联合输注新鲜冰冻血浆、冷沉淀,分析治疗效果。结果观察组治疗2 h内成功止血率97.54%(119/122),高于对照组的75.41%(92/122)(P <0.05);观察组输注红细胞总量及住院时间均低于对照组(P <0.05);观察组治疗后PT、APTT、TT均低于对照组及治疗前(P <0.05);观察组治疗后FIB高于对照组及治疗前(P <0.05)。结论冷沉淀对消化道急性大出血中的应用效果较好,多建议联用新鲜冰冻血浆。
Objective To analyze the application effect ofcryoprecipitate in acute massive hemorrhage of digestive tract.Methods A total of 244 patients with acute gastrointestinal bleedingwho underwent transfusion therapy in our hospital from January2015 to December 2017 were randomized divided into control groupand an observation group, 122 patients in each group. The controlgroup was given fresh frozen plasma, and the observation groupwas given fresh frozen plasma and cryoprecipitate, the therapeuticeffect was analyzed. Results The successful hemostasis rate within2 hours treatment of 97.54% （119/122） in the observation group wassignificantly higher than that of the control group 75.41% （92/122）（P 〈 0.05）, and the total amount of red blood cells and the time ofhospitalization in the observation group were significantly lowerthan that of the control group （P 〈 0.05）. After treatment, PT, APTTand TT in observation group were lower than those in control groupand before treatment （P 〈 0.05）. The FIB of the observation groupafter treatment was higher than that of the control group and beforetreatment （P 〈 0.05）. Conclusion The effect of cryoprecipitationon acute massive hemorrhage of digestive tract is better. It is recommended to use fresh frozen plasma in combination.
作者
伏洪舵
岳茜
朱晓锋
FU Hongduo;YUE Qian;ZHU Xiaofeng(Department of Blood Transfusion,Jiange County People＇s Hospital,Guangyuan Sichuan 628300,China)
出处
《中国继续医学教育》
2018年第31期87-89,共3页
China Continuing Medical Education
关键词
输血治疗
新鲜冰冻血浆
冷沉淀
消化道急性大出血
成分血制品
成分输血
blood transfusion
fresh frozen plasma
cryoprecipitation
acute massive hemorrhage of digestive tract
ingredients blood products
ingredients transfusion
