摘要
目的:探讨3种不同促排卵治疗方案对多囊卵巢综合征促排卵的疗效。方法:选取本院(2015年1月至2017年1月)收治的120例多囊卵巢综合征患者为研究对象,根据不同促排卵治疗方案分为三组,氯米芬组40例患者,人绝经期促性腺激素组40例患者,联合治疗组40例患者,对比三组患者的hCG注射日血清激素水平、成熟卵泡个数、子宫内膜厚度以及妊娠、排卵、卵巢过度刺激综合征、流产发生率。结果:人绝经期促性腺激素组黄体生成素水平明显高于氯米芬组,差异具有统计学意义(P <0.05);氯米芬组和联合治疗组雌二醇水平明显高于人绝经期促性腺激素组,差异具有统计学意义(P <0.05);三组患者睾酮水平对比差异不明显,无统计学意义(P>0.05)。联合治疗组患者成熟卵泡个数明显多于氯米芬组和人绝经期促性腺激素组,差异具有统计学意义(P <0.05);人绝经期促性腺激素组和联合治疗组子宫内膜厚度明显大于氯米芬组,差异具有统计学意义(P <0.05)。人绝经期促性腺激素组与联合治疗组妊娠和排卵发生率对比差异不明显,无统计学意义(P>0.05);人绝经期促性腺激素组与联合治疗组妊娠和排卵发生率明显高于氯米芬组,差异具有统计学意义(P <0.05);人绝经期促性腺激素组卵巢过度刺激综合征发生率明显高于联合治疗组,差异具有统计学意义(P <0.05);三组患者流产发生率对比差异不明显,无统计学意义(P>0.05)。结论:氯米芬联合人绝经期促性腺激素治疗多囊卵巢综合征促排卵效果显著,能降低卵巢过度刺激综合征发生率,促进妊娠率提高。
Objective：To investigate the efficacy of 3 different ovulation induction protocols on ovulation induction in patients with polycystic ovary syndrome. Methods： 120 patients with polycystic ovary syndrome treated in our hospital （January 2015 to January 2017） were selected and divided into three groups, 40 cases of clomiphene group, 40 cases of human menopause gonadotropin group, 40 patients in the combined treatment group, and the comparison of the three groups of patients with serum hormone injection day. Levels, number of mature follicles, endometrial thickness, pregnancy, ovulation, ovarian hyperstimulation syndrome, and incidence of miscarriage. Results： The level of luteinizing hormone in the human menopause gonadotropin group was significantly higher than that in the clomiphene group （ P 〈 0.05）. The estradiol levels in the clomiphene group and the combined treatment group were significantly higher than those in the human menopause gonadotropin group, the difference was statistically significant （ P 〈 0.05）; the differences in testosterone levels in the three groups were different. It was not significant and was not statistically significant （ P 〉 0.05）. The number of mature follicles in the combined treatment group was significantly more than that in the clomiphene group and the human menopause gonadotropin group. The difference was statistically significant （ P 〈 0.05）. The endometrium thickness of the human menopause gonadotropin group and the combined treatment group was significantly greater than that in the clomiphene group （ P 〈 0.05）. There was no significant difference in the incidence of pregnancy and ovulation in the human menopause gonadotropin group and the combined treatment group （ P 〉 0.05） . The incidence of pregnancy and ovulation in the human menopause gonadotropin group and the combined treatment group was significantly higher than that in the clomiphene group （ P 〈 0.05）; human menopause gonadotropin The incidence of ovarian hyperstimul
作者
罗彩霞
Luo Caixia(Department of Obstetrics and Gynecology,Ezhou Maternal and Child Health Care Hospital of Hubei Province,Ezhou,Hubei,43609)
出处
《中外女性健康研究》
2018年第20期1-2,18,共3页
Women＇s Health Research
关键词
促排卵
多囊卵巢综合征
人绝经期促性腺激素
Ovulation induction
Polycystic ovary syndrome
Human menopause gonadotropin
