摘要
目的 分析北京市东城区5岁以下人群感染性腹泻的病原学特征.方法 通过传染病监测技术平台信息管理系统,以北京市东城区2012—2015年在第二妇幼保健院就诊的感染性腹泻患儿为研究对象,纳入标准为5岁以下且发病3 d内未使用抗生素的门急诊病例,共1 977例;收集其年龄、感染时间、临床症状及实验室检测结果等信息.采用χ^2=验比较不同性别、时间和年龄间患儿腹泻病毒和细菌检出率以及单纯检出病毒和单纯检出细菌者临床特征的差异.结果 1 977例患儿月龄的P50（P25,P75）为14.19（8.31,23.15）,病毒检出率为34.3%（679例）,细菌检出率为14.6%（288例）.不同月龄患儿病毒检出率差异有统计学意义（χ^2=72.38,P〈0.001）,24-60月龄最高,为40.9%（188/460）,0-5月龄组最低,为15.3%（48/314）;不同月龄患儿细菌检出率差异有统计学意义（χ^2=32.67,P〈0.001）,12-17月龄组最高,为19.0%（81/426）,0-5月龄组最低,为6.7%（21/314）.单纯病毒检出组发生呕吐和水样便的比例分别为22.2%（136例）和73.3%（449例）,均高于单纯细菌检出组[8.1%（18例）和57.2%（127例）],差异有统计学意义（χ^2值分别为125.92和19.60,P值均〈0.001）;发生黏液便和发热的比例分别为0.8%（5例）和14.0%（86例）,均低于细菌检出组[4.1%（9例）和18.5%（41例）],差异有统计学意义（χ^2值分别为8.50和23.01,P值分别为0.004和〈0.001）.结论 北京市东城区婴幼儿感染性腹泻病毒检出率高于细菌检出率,而且临床特征存在较大差异.
Objective To analyze the etiological characteristics of infectious diarrhea among people under 5 years old in Dongcheng District, Beijing. Methods The age, time of infection, clinical symptoms and laboratory test results of the cases who didn＇t used antibiotics within 3 days in the second maternal and child health care hospital were collected from 2012 to 2015, through the information management system of infectious disease monitoring technology platform. To compare the detection rate of virus and bacteria in children with different sex, time and age,and the difference of clinical characteristics between virus detection group and bacteria detection group by chi square test. Results 1 977 cases of infectious diarrhea were collected,the median of the month age （P25,P75） was 14.19 （8.31, 23.15） months. The virus detection rate was 34.3% （679 cases）; the bacterial detection rate was 14.6% （288 cases）. The difference of virus detection rate in children with different months was statistically significant （χ^2=72.38, P〈0.001）, the virus detection rate of 24-60 months （40.9% （188/460）） was the hightest, and the detection rate of 0-5 months （15.3% （48/314）） was the lowest. The difference of bacteria detection rate was also statistically significant （χ^2=32.67,P〈0.001）, and the detection rate of 12-17 months （19.0% （81/426）） was the highest, the detection rate of 0-5 months （6.7% （21/314）） was the lowest. The proportion of vomit and water sample in the virus detection group was 22.2% （136 cases） and 73.3% （449 cases）, respectively, which were higher than those in bacteria detection group （8.1% （18 cases） and 57.2% （127 cases））, the difference was statistically significant （χ^2 values were 125.92 and 19.60; P values were both〈0.001）; the proportion of mucus stool and fever was 0.8% （5 cases） and 14.0% （86 cases）, respectively, which were lower than those in bacterial detection group （4.1% （9 cases） and 18.5% （41 cases�
作者
王联君
周莹
祁亮
梁俊荣
孙昊
许宝麟
汪静
王鑫
景怀琦
Wang Lianjun;Zhou Ying;Qi Liang;Liang Junrong;Sun Hao;Xu Baolin;Wang Jing;Wang Xin;Jing Huaiqi(Dongcheng District Center for Disease Control and Prevention,Beijing 100009,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2018年第9期936-940,共5页
Chinese Journal of Preventive Medicine
关键词
病原
腹泻
感染
婴幼儿
Noxae
Diarrhea
Infection
Infants
