摘要
目的了解深圳市龙岗区感染性腹泻的病原谱特征,为制定防控措施提供依据。方法通过深圳市疾病控制信息系统,收集龙岗区2家哨点医院上报的感染性腹泻监测数据,分析其病原构成、季节变化和人群分布。结果 1 182份标本中523份检出病原,检出率为44.25%。致病菌检出率明显高于病毒检出率(30.54%vs.14.72%),差异有统计学意义(χ~2=84.48,P=0.00),约0.93%的标本为双重或多重感染。夏秋季以细菌性病原检出为主,冬春季则以病毒检出较为常见;不同年龄段人群感染性腹泻病原构成有所不同(χ~2=12.76,P=0.01);越早采样标本阳性检出率越高(χ~2=12.76,P=0.01),多重临床表现患者的检出率高于单一临床表现的患者(χ~2=14.76,P=0.00)。结论深圳市龙岗区感染性腹泻病原谱以沙门菌、诺如和轮状病毒为主,病原谱已发生变化,应加强监测,做好不同季节重点人群的防控工作。
Objective To understand the characteristics of the pathogens of infectious diarrhea in Longgang district,andprovide scientific basis for the prevention and control of infectious diarrhea.Methods Surveillance data of infectiousdiarrhea from two sentinel hospital were collected from the Disease Control Information Systemof Shenzhen for the analysisof its pathogenic composition,seasonal changes and population distribution.Results Total 523 pathogens were detectedin 1 182 specimen,with a detection rate of 44.25%.The detection rate of pathogenic bacteria（30.54%）was higher thanthat of virus（14.72%）,and 0.93% of the specimens were double or multiple infections.Bacterial pathogens were mainlydetected in summer and autumn,but virus detection was more common in winter and spring,and the pathogeniccomposition of infectious diarrhea were different among age groups（χ~2=12.76,P=0.01）.The earlier the sample was taken,the higher the positive detection（χ~2=12.76,P=0.01）,and the detection rate of patients with multiple clinicalmanifestations was higher than that of patients with a single clinical presentation（χ~2=14.76,P=0.00）.Conclusion Thepathogenic spectrum of infectious diarrhea in Longgang district of Shenzhen was dominated by Salmonella,Noro,andRotavirus,and the pathogen spectrum had changed.Monitoring should be strengthened to prevent and control keypopulations in different seasons.
作者
杨永平
刘凤仁
刘渠
金玉娟
李刚
YANG Yong-ping;LIU Feng-ren;LIU Qu;JIN Yu-juan;LI Gang(Pingdi,Longgang District,Shenzhen to Preevent,Health-Care Station,Shenzhen,Guangdong 518117;Longgang District Center for Disease Control and Prevention,Shenzhen,Guangdong 518116,China)
出处
《热带医学杂志》
CAS
2018年第7期977-980,共4页
Journal of Tropical Medicine
关键词
感染性腹泻
病原谱
龙岗
Infectious diarrhea
Pathogen spectrum
Longgang
