摘要
目的了解海口地区感染性腹泻致病菌病原谱构成情况和流行病学特征,为防治工作提供科学依据。方法将2014-2016年每年的5~10月在海口地区各监测点医院送检的384份感染性腹泻患者粪便标本,通过增菌、培养、生化分析及血清凝集实验进行菌株鉴定,同时填写流行病学调查表,了解患者信息。结果 384份感染性腹泻患者粪便标本检出病原菌104株,阳性率为27.08%。其中副溶血弧菌位居所有检出菌的首位(66.35%,69/104),其次是气单胞菌(16.35%,17/104)、河弧菌(3.85%,4/104)。患者主要集中在20~50岁(79.4%,305/384),病原菌的检出具有明显的季节性,7月是高峰。结论海口地区的感染性腹泻由多种病原体引起,病原菌的分布与患者年龄和季节存在关联,因此加强对腹泻的流行病学监测和扩大病原菌监测范围对感染性腹泻的防控至关重要。
Objective To understand the pathogenic spectrum and epidemiological characteristics of infectious diarrhea in Haikou and provide scientific evidence for the prevention and control work. Methods A total of 384 stool specimens collected from May to Oct. in 2014-2016 from infectious diarrhea patients in different monitoring sites,which were detected by the isolation culture, biochemical identification and serotyping methods. The epidemiological questionnaire was used to survey the patients＇ information. Results Among the 384 stool specimens, 104 strains of pathogenic bacteria were detected, with the positive rate of 27.08%. Vibrio parahaemolyticus was the most frequently pathogen, accounting for 66.35%（69/104）, followed by Aeromonas, accounting for 16.35%（17/104）, and Vibrio fluvialis,accounting for 3.85%（4/104）. Most of patients were aged 20-50 years old（79.4%, 305/384）. There was obvious seasonality in the positive detection of pathogens, and the peak time was July. Conclusion Infectious diarrhea in Haikou area is caused by many kinds of pathogens. The distribution of pathogens is related to the patient＇s age and season. Therefore, it＇s important to strengthen the epidemiological surveillance of diarrhea and increase the scale of pathogenic surveillance for the prevention and control of the disease.
作者
陈小佳
王琼妹
聂绍发
CHEN Xiao-jia;WANG Qiong-mei;NIE Shao-fa(School of Public Health, Tongfi Medical College of Huazhong University of Science and Technology, Wuhan 430030, Hubei, CHINA;Haikou City Center for Disease Control and Prevention, Haikou 571100, Hainan, CHINA)
出处
《海南医学》
CAS
2018年第13期1902-1904,共3页
Hainan Medical Journal
关键词
海口
感染性腹泻
病原谱
流行病学特征
Haikou
Infectious diarrhea
Pathogenic spectrum
Epidemiological features
