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探讨同型半胱氨酸、非高密度脂蛋白胆固醇与高血压患者中医证型关系的研究 被引量:4

Relationship of HCY and NHDL with TCM Syndrome in Patients with Hypertension
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摘要 目的:探讨同型半胱氨酸(HCY)、非高密度脂蛋白胆固醇(non-HDL-c)与高血压患者中医证型关系。方法:将2017年3月—2017年10月间在安徽中医药大学第一附属医院老年心内科病房高血压患者203例纳入研究,分析中医证型,检测并比较各证型患者总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、血清同型半胱氨酸(HCY),非高密度脂蛋白胆固醇。结果:203例患者中以阴虚阳亢HCY和non-HDL-C水平最高,与其他组比较有统计学意义(P <0. 05或P <0. 01)。结论:高血压患者中辨证为阴虚阳亢证、痰湿壅盛证的患者心脑意外事件发生率较高,提示高血压患者中医临床治疗过程中需注重平肝潜阳、健脾化湿之法,尤其要注意阴津亏损,阳气失去制约为发病基础的人群,存在较高的血栓性事件风险。 Objective : To investigate the relationship of homocysteine(HCY) and non -high -density lipoprotein choles-terol( N - HDL - C) with TCM syndrome in patients with hypertension. Methods : 203 hypertentsion cases were includedin the study. TCM syndrome was analyzed ; TC, HDL - C, LDL - C, HCY, and N - HDL - C were detected and corn-pared in hypertension patients with different TCM syndromes. Results : The levels of HCY and N - HDL - C were highestin the syndome of Yin Deficiency with Yang hyperactivity among 203 cases. Conclusion : Cardiovascular and cerebrovas-cular accidents were mostly happened in the hypertension patients with the syndrome of Yin deficiency and Yang hyper-activity, or with the syndrome of congested dampness - phlegm ; therefore the therapies of pacifying the Liver to subdueYang, as well as reinforcing the Spleen to resolve dampness should be paid attention to; patients should especially be paidmore attention to are those with loss of Yin fluids and Yang failing to be controlled, who are mostly prone to thrombosis.
作者 何佳 姚淮芳 程晓昱 崔萌萌 任文杰 乔敖 HE Jia;YAO Huaifang;CHENG Xiaoyu;CUI Mengmeng;REN Wenjie;QIAO Ao(The First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230031,China;Anhui University of Chinese Medicine,Hefei 230012,China;Qizili Town Hospital of She County,Huangshan 245211,China;Meixi Township Central Hospital of Yi County,Huangshan 245500,China)
出处 《中医药学报》 CAS 2018年第5期111-114,共4页 Acta Chinese Medicine and Pharmacology
基金 安徽中医药大学校级课题(2015fy002)
关键词 高血压 非高密度脂蛋白 同型半胱氨酸 中医证型 Hypertension N - HDL - C Homocysteine TCM syndrome
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