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经尿道前列腺电切术结合中医特色疗法及加速康复外科理念对血流变学、炎性因子、T细胞亚群变化的影响 被引量:5

Effects of transurethral prostatectomy combined with traditional Chinese medicine characteristic therapy and the concept of accelerated rehabilitation surgery on hemorheology,inflammatory factors and T cell subsets
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摘要 目的探讨经尿道前列腺电切术结合中医特色疗法及加速康复外科理念对血流变学、炎性因子、T细胞亚群变化的影响。方法经尿道前列腺电切术的患者80例,摸球法随机分为两组,每组40例。常规组采用经尿道前列腺电切术采用常规护理,特色组在常规组的基础上加用耳穴压豆、体穴针刺中医特色康复治疗。观察两组患者术后首次肛门排气时间、术后并发症发生情况、术后住院天数。术前、术后7天抽晨起静脉血检测血流变学,白介素-6、白介素-8、白介素-10、白介素-17、肿瘤坏死因子-α、C反应蛋白水平及T细胞亚群变化。所获数据采用方差分析、t检验及Ridit分析。结果两组术后12 h疼痛指数、术后膀胱痉挛率、首次排气时间、住院天数比较P<0.05~0.0005。同组及两组术前、后血浆黏度、高切黏度、中切黏度、低切黏度、红细胞聚集指数、纤维蛋白原变化比较,P均>0.05。两组术后7天血浆黏度、高切黏度、中切黏度、低切黏度、红细胞聚集指数、纤维蛋白原变化比较,P均>0.05。两组同组术前、术后第7天白介素-6、白介素-8、白介素-10、白介素-17、肿瘤坏死因子-α、C反应蛋白水平比较,P均<0.0005。两组术后第7天白介素-6、白介素-8、白介素-10、白介素-17、肿瘤坏死因子-α、C反应蛋白水平比较,P均<0.0005~0.001。常规组术前、术后7天CD_3^+、CD_4^+、CD_8^+、CD_4^+/CD_8^+、CD_4^+CD25+、CD_4^+CD_(25)^-水平变化,P均<0.05~0.0005。特色组术前、术后7天CD_3^+、CD_4^+、CD_8^+、CD_4^+/CD_8^+、CD_4^+CD25+、CD_4^+CD_(25)^-水平变化,P均<0.05~0.0005;特色组术前、术后7天CD_4^+/CD_8^+水平变化,P>0.05。两组术后7天CD_3^+、CD_8^+·、CD_4^+CD25+、水平变化,P均<0.05~0.0005;两组术后7天CD_3^+、CD_8^+、CD_4^+CD_(25)^-水平变化,P均>0.05。结论经尿道前列腺电切术围术期应用耳穴压豆、体穴针刺可加速患者康复、减少术后并发症 Objective To explore the effect of transurethral prostatectomy combined with traditional Chinese medicine characteristic therapy and the concept of accelerated rehabilitation surgery on the changes of hemorheology, inflammatory factors and T cell subsets. Methods 80 patients with transurethral prostatectomy were randomly divided into two groups with 40 cases in each group. The conventional group was treated by transurethral prostatectomy with routine nursing,and the characteristic group was treated with characteristic rehabilitation treatment of traditional Chinese medicine based on the conventional group. The first postoperative anal discharge time, postoperative complications and postoperative hospitalization days were observed. Preoperative and postoperative venous blood since morning 7 day detecting hemorrheology, interleukin 6 and interleukin 8, interleukin 10, interleukin 17, tumor necrosis factor alpha, c-reactive protein level and the change of T cell subgroup. The obtained data were analyzed by anova, t test and Ridit analysis. Results Comparison of postoperative 12 h pain index, postoperative bladder spasm rate, first exhaust time and length of stay between the two groups was P〈0.05^0.0005. Comparison of plasma viscosity, high shear viscosity, medium shear viscosity, low shear viscosity, erythrocyte aggregation index and fibrinogen changes between the same group and the two groups before and after surgery, P〉0.05. Plasma viscosity, high shear viscosity, medium shear viscosity, low shear viscosity, erythrocyte aggregation index and fibrinogen changes were compared between the two groups 7 days after surgery, all P〉0.05. Comparison of interleukin-6, interleukin-8, interleukin-10, interleukin-17, tumor necrosis factor-alpha and c-reactive protein levels between the two groups on the7 th day before and after surgery was conducted, P〈0.0005. Comparison of interleukin-6, interleukin-8, interleukin-10, interleukin-17, tumor necrosis factor-alpha and c-reactive protein levels on day 7 after surgery betw
作者 张霞 Zhang Xia(Linyi central blood station,Linyi 276000,Shandon)
机构地区 临沂市中心血站
出处 《菏泽医学专科学校学报》 2018年第2期60-63,75,共5页 Journal of Heze Medical College
关键词 经尿道前列腺电切术 加速康复外科 护理 耳穴压豆 体穴针刺 血流变学 炎性因子 T细胞亚群 Transurethral prostatectomy Accelerated rehabilitation surgery Nursing Ear pressing bean Body acu-puncture Hemorheology Inflammatory factors T cell subgroup
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