摘要
目的探讨综合性护理干预在难治性免疫性血小板减少症患者中的应用及对患者免疫系统功能的影响。方法选择本院收治的70例难治性免疫性血小板减少症患者为研究对象,应用随机数表法分为对照组和观察组各35例。2组均接受部分脾动脉栓塞手术治疗,对照组行常规护理,观察组应用综合性护理干预。观察患者术前、术后1个月后2组免疫系统功能变化情况,术后3个月行疗效评估,记录并发症发生情况。结果术前2组免疫功能指标水平差异无统计学意义(P>0.05);术后1个月,2组CD3^+、CD4^+和CD4^+/CD8^+等指标水平均高于术前,CD8^+水平低于术前,观察组指标水平均高于对照组,CD8^+水平低于对照组,差异有统计学意义(P<0.05)。护理后,观察组患者的治疗总有效率88.57%高于对照组的68.57%(P<0.05);观察组护理期间穿刺部位出血、感染、胃肠道反应、呼吸系统反应等并发症总发生率8.57%低于对照组的22.86%(P<0.05)。结论难治性免疫性血小板减少症患者中应用综合性护理干预效果显著,可有效减轻手术应激,改善患者免疫系统功能,降低术后并发症发生率,增强手术治疗效果,促进患者术后恢复。
Objective To study application of comprehensive nursing intervention in patients with refractory immune thrombocytopenia and its effect on patients’ immune system function.Methods A total of 70 patients with refractory immune thrombocytopenia treated in our hospital were divided into control group with 35 cases and observation group with 35 cases according to random number table method. Both groups received surgical treatment of partial splenic artery embolization.The control group received routine nursing care during the perioperative period,while the observation group received comprehensive nursing intervention. The changes in immune system function in preoperation and postoperative one-month of two groups were observed,and the efficacy at 3 months after nursing were evaluated. The occurrence of complications during the reasonable period was recorded.Results There was no significant difference in the level of immune function between the two groups before surgery（ P 〉 0. 05）. At 1 month after operation,the levels of CD3~＋,CD4~＋and CD4~＋/CD8~＋were higher,and the level of CD8~＋was lower than surgery before,the levels of CD3~＋,CD4~＋and CD4~＋/CD8~＋in the observation group was higher than that of the control group,and the level of CD8~＋was lower than that of the control group（ P 〈 0. 05）. After treatment,the total effective rate of treatment in the observation group was 88. 57%,which was higher than 68. 57% in the control group（ P 〈 0. 05）. The total incidence of complications such as infection,gastrointestinal reactions,and respiratory system reactions was 8. 57%,which was lower than 22. 86% in the control group（ P 〈0. 05）. Conclusion Comprehensive nursing intervention for patients with refractory immune thrombocytopenia shows significant efficacy,which can effectively reduce surgical stress,improve function of immune system,reduce the incidence of postoperative complications,enhance efficacy of surgical treatment,and promote postoperative rehabilitation.
作者
孟欢
MENG Huan(Department of Surgery,Tuanfeng County People’s Hospital of Huanggang City, Huanggang, Hubei, 43880)
出处
《实用临床医药杂志》
CAS
2018年第18期39-42,共4页
Journal of Clinical Medicine in Practice
关键词
免疫性血小板减少症
综合性护理干预
免疫系统功能
immune thrombocytopenia
comprehensive nursing intervention
immune system function
