摘要
目的探讨冠状动脉造影与血流储备分数(FFR)在稳定型冠心病(CAHD)患者经皮冠状动脉介入治疗(PCI)治疗中的效果。方法选择120例稳定型CAHD患者,随机分为对照组与研究组各60例。对照组采用冠状动脉造影作为指导,并参照美国心血管造影和介入学会(SCAI)/美国心脏病学会(ACC)/美国心脏学会(AHA)PCI治疗指南,决定是否采取常规冠状动脉PCI治疗。研究组患者在行冠状动脉造影的同时测定冠状动脉病变处FFR,若FFR≤0.8,在狭窄病变处植入药物洗脱支架,术后再次测定FFR,若仍≤0.8则在病变处实施支架内球囊扩张术。对比2组患者PCI治疗率、人均植入支架数目、手术时间、造影剂用量及人均治疗费用,以及1年内心血管不良事件的发生情况。结果研究组PCI治疗率46.67%,显著低于对照组60.00%(P<0.05),研究组人均植入支架数目、造影剂用量及人均治疗费用均显著低于对照组(P<0.05);2组手术时间无显著差异(P>0.05)。2组患者1年内急性心肌梗死、再次血运重建、复发心绞痛发生率比较,差异无统计学意义(P>0.05)。结论冠状动脉造影联合FFR对稳定型CAHD患者PCI治疗具有重要的指导意义。
Objective To investigate the effect of coronary angiography and fractional flow reserve （FFR） on the treatment of patients with stable coronary artery disease （CAHD） by percutaneous coronary intervention （PCI）. Methods A total of120 patients with stable CAHD were selected and randomly divided into control group and study group, 60 cases in each group. The control group was treated by coronary angiography, and was conducted with PCI according to the American angiocardiography and interventional Association （SCAI）/American Heart Disease Association （ACC）/American Heart Association （AHA） guidance. and the patients were implanted with drug eluting stents at the lesion site. In the study group, FFR was measured by coronary artery angiography. If the index was less than 0.8, the drug eluting stent was implanted in the stenosis and the FFR was measured again after the operation. The balloon dilatation was performed in the stent if FFR was still less than 0.8. The ratio of PCI treatment, the per capita number of implanted stents, the time of operation, the amount of contrast agent and the per capita cost of treatment were compared between the two groups, and the incidence of adverse events in one year was also recorded. Results The ratio of PCI treatment in the study group was 46.67%, which was significantly lower than 60.00% of the control group （ P 〈0.05）. The number of stent implantation, the amount of contrast agent and the per capita cost of treatment in the study group were significantly lower than those in the control group （ P 〈0.05）, but there was no significant difference in operation time between the two groups （ P 〉 0.05）. There was no significant difference in the incidence rates of complications such as acute myocardial infarction, revascularization and recurrent angina in one year between the two groups （ P 〉0.05）. Conclusion Coronary angiography combined with FFR has an important guiding significance for stable CAHD patients with PCI treatment.
作者
席新龙
王君
XI Xinlong;WANG Jun(Department of Cardiac Intervention,Xi＇an First Hospital,Xi＇an,Shaanxi,710002)
出处
《实用临床医药杂志》
CAS
2018年第15期29-32,共4页
Journal of Clinical Medicine in Practice
关键词
冠状动脉造影
血流储备分数
稳定型冠心病
介入治疗
coronary angiography
fractional flow reserve
stable coronary heart disease
interventional therapy
