摘要
近年研究发现,microRNA 21表达水平的变化与心血管疾病病理演变的多个方面存在相关性,包括动脉粥样硬化、心肌缺血后再灌注损伤、心室重构的演变及终末期心力衰竭等进程。现就近年国内外关于microRNA 21参与调控冠心病相关病理进程的研究进展进行综述,为冠心病的认知和研究提供新的思路。
In recent years,research studies have found that the changes of microRNA 21 expression correlate with multiple aspects of the pathological changes of cardiovascular diseases and are involved in the process of atherosclerosis, myocardial ischemia repeffusion injury, evolution of ventricular remodeling and end-stage heart failure. In this paper, we reviewed the progress of microRNA 21 in the pathogenesis of coronary heart disease in recent years and provide new ideas for the cognitive and research of coronary heart disease.
作者
张倩
宋林声
赵新湘
ZHANG Qian;SONG Linsheng;ZHAO Xinxiang(Kunming Medical University Graduate School,Kunming 650000,Yunnan,China;Department of Radiology,The Second Affiliated Hospital of Kunming Medical University,Kunming 650101,Yunnan,China)
出处
《心血管病学进展》
CAS
2018年第4期598-601,共4页
Advances in Cardiovascular Diseases