摘要
目的:探索疏肝益阳胶囊应用于手淫取精困难患者的疗效和安全性。方法:将58例手淫取精困难患者随机分为疏肝益阳胶囊联合行为疗法组(治疗组,30例)和单用行为疗法组(对照组,28例)。对照组在进入体外受精-胚胎移植(in vitro fertilization-embryo transfer,IVF-ET)助孕周期前1~3个月练习手淫取精。治疗组不仅练习手淫取精,且提前4~6周口服疏肝益阳胶囊至女方行取卵手术前一日。结果:治疗组和对照组患者的年龄分别为(37.13±6.04)岁和(36.54±5.63)岁,其差异无统计学意义(P>0.05)。治疗组23例手淫取精成功,成功率为76.67%(23/30);对照组13例手淫取精成功,成功率为46.43%(13/28)。χ~2检验显示,两组差异具有统计学意义(χ~2=5.63,P<0.05)。治疗组患者治疗后的精液指标(精液量、精子浓度、活动率、前向运动精子百分率)比治疗前有所提高,其差异无统计学意义(P>0.05)。两组患者的受精率、卵裂率、优胚率、配偶妊娠率等指标的差异均无统计学意义(均P>0.05)。结论:疏肝益阳胶囊可以提高手淫取精困难患者的取精成功率,且具有良好的安全性,可以作为取精困难患者的一种有效疗法。
Objective： To study the efficacy and safety of Shugan Yiyang capsule in improving the success rate of semen collection of infertile men with masturbation difficulty. Methods： 58 male infertile patients with masturbation difficulty were randomly assigned to receive Shugan Yiyang capsule combined with behavior therapy（ treatment group,n = 30） and behavior therapy only（ control group,n = 28）. The control group was trained to masturbate for 1 to 3 months before entering the IVF cycle. Treatment group not only practiced masturbation training,but also took Shugan Yiyang capsule for at least 4 ~ 6 weeks. Results： The age between the treatment group of（ 37. 13± 6. 04） years old and the control group of（ 36. 54 ± 5. 63） years old was not significantly different（ P〉0. 05）.The success rate of semen collection was 76. 67%（ 23/30） in the treatment group which was significantly higher than that of the control group of 46. 43%（ 13/28）,（ χ~2= 5. 63,P〈0. 05）. The semen parameters including semen volume,sperm concentration,total motility and progressive motility of treatment group were improved,without statistically significant difference（ P〉0. 05）. There were no significant differences in fertilization rate,cleavage rate,good-quality embryo rate and pregnancy rate between the two groups（ all P〉0. 05）. Conclusions： Shugan Yiyang capsule is safe and effective in improving the success rate of semen collection in patients with masturbation difficulty.
作者
薛瑜
廖明
覃爱平
XUE Yu;LIAO Ming;QIN Aiping(Research Center for Reproductive Medicine,The First Affiliated Hospital of Guangxi Medi- cal University,Nanning 530021,Guangxi,China)
出处
《中国性科学》
2018年第5期36-39,共4页
Chinese Journal of Human Sexuality
基金
广西壮族自治区自然科学基金项目(2014GXNSFAA118189)
关键词
疏肝益阳胶囊
手淫取精
取精困难
体外受精-胚胎移植
Shugan Yiyang capsule
Ejaculation by masturbation
Ejaculation failure
In vitro fertilization-embryo transfer （IVF-ET）
