摘要
目的观察清金化痰汤加减治疗痰热壅肺型老年社区获得性肺炎(CAP)的临床疗效及其对血清CRP和IL-6、IL-10的影响。方法将64例老年CAP患者采用随机数字表法分为对照组和治疗组。对照组采用常规抗感染及对症支持治疗,治疗组在对照组基础上加用清金化痰汤,疗程为10 d。观察并记录2组患者治疗前后总有效率、临床症状积分及血清CRP和IL-6、IL-10的水平变化情况。结果治疗组总有效率为90.63%(29/32)高于对照组84.38%(27/32)(P<0.05);治疗后,治疗组中医症状积分均低于对照组(P<0.05);治疗组CRP及IL-6、IL-10水平均优于对照组(P<0.05)。结论清金化痰汤加减治疗痰热壅肺型老年CAP临床疗效显著,能够改善临床症状,降低血清CRP和IL-6、IL-10炎性因子的水平。
Objective To observe the clinical effect of Qingjin Huatan decoction in the treatment of elderly community-acquired pneumonia with phlegm-heat syndrome and its effect on serum CRP, IL-6 and IL-10. Methods 64 elderly patients with CAP were divided into control group and treatment group by random number table. The control group was treated with conventional antiinfection and symptomatic supportive treatment, treatment for 10 days. The treatment group was treated with Qingjin Huatan decoction on the basis of the control group. The changes of total effective rate, clinical symptom scores, serum CRP, IL-6 and IL-10 levels before and after treatment were observed and recorded in both groups. Results The total effective rate in the treatment group and control group was 90.63% and 84.38% respectively, and there had significant difference between the two groups（P〈0.05）.After treatment, the TCM symptom scores in the treatment group were lower than those in the control group（P〈0.05）. The levels of CRP, IL-6 and IL-10 in the treatment group were better than those in the control group（P〈0.05）. Conclusion The clinical curative effect of Qingjin Huatan decoction in the treatment of phlegm-heat lung-type elderly CAP is significant, which can improve the clinical symptoms and reduce the levels of serum CRP, IL-6 and IL-10.
作者
韩秋盈
孟泳
甘德堃
HANG Qiuying;MENG Yong;GAN Dekun(The Second Clinical Medical College, Henan University of Traditional Chinese Medicine, Henan Province, Zhengzhou 450002, China;Department of Pulmonary Disease, Henan Provincial Hospital of Traditional Chinese Medicine, Henan Province, Zhengzhou 450002, China)
出处
《中国中医药现代远程教育》
2018年第11期100-102,共3页
Chinese Medicine Modern Distance Education of China
关键词
老年科
社区获得性肺炎
清金化痰汤
炎性因子
咳嗽
geriatrics
community-acquired pneumonia
Qingjin Huatan decoction
inflammatory factor
cough
