摘要
目的:了解某三级甲等综合医院(以下简称"该院")质子泵抑制剂的使用情况,为优化医院药品目录和制订药物临床合理使用规范提供依据。方法:对2015—2017年该院质子泵抑制剂的使用数据进行回顾性统计分析,计算各药的销售金额、用药频度、限定日费用和药品销售金额排序(B)/用药频度排序(A)的比值,并对典型病例进行用药合理性评价。结果:2015—2017年该院口服质子泵抑制剂中,使用频率最高的是雷贝拉唑钠肠溶胶囊(20 mg),其B/A>1,经济性较好;静脉用质子泵抑制剂的限定日费用均较高,且B/A<1,经济性较差。心导管射频消融术后使用质子泵抑制剂预防心房食管瘘是合理的。结论:以医院药品数据为基础,结合病例进行用药合理性分析,可以为优化医院药品目录、制订医院药物临床合理使用规范提供参考。
OBJECTIVE： To investigate the application of proton pump inhibitors in a 3-A grade hospital （ hereinafter referred to as ＂this hospital＂ ）, so as to provide basis for formulating regulations of proton pump inhibitors and references for clinical rational medication. METHODS ： Respective analysis was conducted on application of proton pump inhibitors in the hospital during 2015-2017, including consumption sum, defined daily dose system （DDDs） , defined daily cost（DDC） and B/A; rationality evaluation was conducted on typical cases. RESULTS： During 2015- 2017, the most frequency oral proton pump inhibitors was Rabeprazole sodium enteric-coated capsules （20 mg） , andthe economy was better for B/A 〉 1. The DDc of proton pump inhibitors for veins was relatively high, and the economy was poorer for B/A 〈 1. It is rational to apply proton pump inhibitors for the prevention of atrial esophageal fistula after radiofrequency catheter ablation. CONCLUSIONS： Based on the data of the hospital drugs, eombined with the rationality analysis of ease medication, it can provide references for optimizing the hospital drug catalogue and formulating the clinical rational use standard o~ hospital drugs.
作者
张喆
胡敏
楚明明
张蓉
ZHANG Zhe, HU Min, CHU Mingming, ZHANG Rong(Dept. of Pharmacy, the Second Affiliated Hospital of Army Medical University, Chongqing 400037, Chin)
出处
《中国医院用药评价与分析》
2018年第5期663-665,670,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
陆军军医大学第二附属医院临床科研基金项目(No.2016YLC25)
关键词
质子泵抑制剂
用药分析
合理用药
Proton pump inhibitors
Drug analysis
Rational drug use
