摘要
血清雌激素(E_2)水平是评估控制性促排卵(COS)中卵泡发育及对促性腺激素(Gn)反应的重要指标。E_2水平的下降能否预测妊娠结局,目前尚无定论。本文分析了1例促性腺激素释放激素拮抗剂(GnRH-A)促排卵方案中出现E_2下降的案例,患者的获卵率明显下降,受精率和卵裂率正常,仅获得1枚优质胚胎,未成功妊娠,因此GnRH-A方案中E_2下降,可能会导致卵母细胞回收率下降。
Serum estradiol （E：） levels is an important marker for evaluating follicular development and response to gonadotropins in controlled ovarian stimulation （COS）. Whether the decline in E2 levels can predict outcomes still remains inconclusive. The study analyzed a case of drop in estradiol in the gonadotropin releasing hormone antagonist （GnRH-A） protocol. In the case, the patient had decreasing oocyte rates significantly, normal fertilization rates and normal cleavage rates, finally an excellent embryo but not pregnancy. So the decrease of E2 in the GnRH-A protocol may lead to a decrease in the recovery rate of oocyte.
作者
李彩华
吴欢
周平
曹云霞
Li Caihua;Wu Huan;Zhou Ping;Cao Yunxia(Reproductive Medicine Center, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Anhui Province Key Laboratory of Reproductive Health and Genetics, Hefei 230000, Chin)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2018年第3期232-234,共3页
Chinese Journal of Reproduction and Contraception
关键词
拮抗剂方案
雌二醇下降
临床结局
Antagonist protocol
Estradiol （E2） decline
Clinical outcome
